A millimeter-sized tubular motor for mobile biosensing of H2O2 in environmental and relevant clinical samples is reported. The concept relies on the self-propelled motion by the Marangoni effect, where the asymmetric release of SDS surfactant induces fluid convection and rapid dispersion of horseradish peroxidase (HRP) enzyme into the sample solution. This efficient movement together with the continuous release of fresh enzyme leads to greatly accelerated enzymatic reaction processes without the need of external stirring or chemical and physical attachment of the enzyme as in common classical biosensing approaches. In this strategy, the use of a single millimeter-sized tubular motor during 120 s allows the reliable and accurate quantification of hydrogen peroxide in a set of different matrices such as tap and mineral waters, urine, plasma, and tumor cell cultures treated with antineoplasic Cisplatin without any previous sample preparation. Furthermore, detection can be performed electrochemically, optically, and via visual detection, which makes this approach a clear candidate as a point-of-care analytical tool.
The majority of holograms are made using interference of light and computer-generated holograms. In this work we propose a technique in real time to generate digital holograms with a VLSI digital component, being specific FPGA and a liquid crystal device. The digital design with FPGA presents great advantage for its parallel procesing that carry out by its flexible structure, high integration and velocity. The design was verified using the platform MathLab/Simulink and Xilinx System Generator.
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