We study nonclassic solitonic structures on the modified oscillator — chain proposed by Peyrard and Bishop to model DNA. The two DNA's strands are linked together by hydrogen bonds that are modeled by the Morse potential. This Peyrard–Bishop model with inharmonic potential in the optical part of the Hamiltonian gives rise to several nonclassical solutions, i.e., compact-cusp and anti-peak or crowd like soliton solutions. These structures could represent not only local openings of base pairs, but also the inverse process that heals the formation of broken hydrogen bonds.
Sources of variability in defining the normal range for left ventricular (LV) motion from contrast ventriculograms were assessed by comparing the function of 183 normal patients from six sites in three countries. Wall motion was measured using the centreline method at seven regions around the LV contour. The influence of institution, heart rate, age, end diastolic volume, body surface area and gender was evaluated using univariate analysis, and then compared using multivariate regression analysis. Wall motion varied significantly but weakly (|r| < 0.32 for all) with site, gender and body surface area in some regions. Variability was greater within sites than between sites. Wall motion was most similar in the two sites with the largest patient populations (N = 49 and N = 52). Normal LV wall motion is influenced by many factors. The reliable definition of the normal range requires analysis of a large number of subjects. For wall motion, the normal population should comprise closer to 50 subjects than the 10-20 that are commonly referenced.
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