Regional anaesthesia for hernia repair in children: local vs caudal anaesthesiaThe purpose of this study was to compare the effect of local anaesthesia (1_,,4)

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Oral ondansetron decreases vomiting after tonsillectomy in childrenVomiting is a common, unpleasant aftermath of tonsillectomy in children. Intraoperative intravenous ondansetron (OND)

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The aim of this study was to establish whether nitrous oxide has a clinically important effect on postoperative vomiting in children after myringotomy. We studied 320 healthy children of ages 0. Vomiting after general anaesthesia in children is common and may result in considerable postoperative morbidity.This vomiting is of multifactorial aetiology of which nitrons oxide is a possible contributing factor. Nitrous oxide may induce vomiting by causing bowel distension, decreasing gastric motility, increasing middle ear pressure or interacting with endogenous opioid receptors. ~-3Among adults undergoing minor gynaecological surgery, as little as a 10-14 min exposure to N202 has been associated with increased vomiting. 3 Overall, the resuits of adult investigations have been controversial. Both an emetic 2-5 and lack of effect 6-9 have been reported. There have been two paedia~c studies. Pandit et al. failed to demonstrate a difference in vomiting after tonsiUectomy (62% vs 76%). 6 In another study of 104 children, nitrous oxide increased vomiting after myringotomy from 4% to CAN J ANAESTH 1995 / 42:4 / pp 274-6

The effect of nitrous oxide on postoperative vomiting was evaluated in 330 children who underwent outpatient dental restorations. There were two groups in this single-blind, randomized, controlled study. One group received nitrous oxide during their anesthetic, while the non-nitrous oxide group did not receive nitrous oxide at any time. Anesthesia was induced by inhalation with halothane or with propofol intravenously. The incidence of vomiting for 24 h after surgery was recorded. Overall, the incidence of vomiting was similar, with 30% of the control patients and 35% of the nitrous-treated patients vomiting after their anesthetic. However, in-hospital vomiting was less in the control group: 15% vs 24%, control versus nitrous oxide, P = 0.03. In conclusion, nitrous oxide does not alter postoperative vomiting after halothane anaesthesia for dental restorations in children.

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