Quantifying CAC using ACCT images appears to be feasible and accurate. In a single cardiac PET examination, information regarding perfusion, LV function, flow quantification, and CAC can be obtained without additional radiation.
In this single-center study, the use of Tl-201 during the Tc-99m shortage was associated with an increase in downstream testing, cost, and patient radiation exposure, but these findings may not be generalizable to other centers. Although Tl-201 provided a short-term solution to the unexpected Tc-99m shortage, long-term cost-effective solutions should be areas of future study.
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