This population-based study has demonstrated the applicability of a new NGS high-risk HPV assay for primary cervical cancer screening based on self-collection.

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This research aimed to compare antioxidant and anticancer activities of the essential oil from various habitats of Selaginella doederleinii Hieron. The results showed that antioxidative activities of the essential oil were the best from Guizhou province in 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS) radical scavenging, ferric reducing and ferric reducing antioxidant power (FRAP), while those of the essential oil from Sichuan province were the weakest among different habitats. The anticancer results showed that antitumor effects of the essential oil from Guizhou province were the best against A549 cell line and 7721 cell line, while those of the essential oil from Sichuan province were the weakest among different habitats. Proliferative and antioxidant activities were correlated. The correlation coefficients (R2) between antioxidant and anticancer capacities varied from 0.71 to 0.94. The results of tests indicated that the antioxidant and anticancer activities of the essential oil from various habitats were great differences that might be affected by environmental variation, harvest seasons and so on. Investigation in vitro revealed that the essential oil of S. doederleinii were found to be effective in suppressing the oxidative activity and proliferation of cancer cells. This experiment provides scientific foundation for further utilization of S. doederleinii.

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Using D,L‐lactic acid (LA) and multifunctional group compound triethanolamine (TEA) as starting materials, a novel biodegradable material poly(D,L‐lactic acid‐triethanolamine) [P(LA‐TEA)] was directly synthesized by simpler and practical melt polycondensation. The appropriate synthetic condition was discussed in detail. When the molar feed ratio LA/TEA was 30/1, the optimal synthesis conditions were as follows: a prepolymerization time of 12 h; 0.5 weight percent (wt %) SnO catalyst; and melt copolycondensation for 8 h at 160°C, which gave a novel star‐shaped poly(D,L‐lactic acid) (PDLLA) modified by TEA with the maximum intrinsic viscosity [η] 0.93 dL g−1. The copolymer P(LA‐TEA) as a different molar feed ratio was characterized by [η], Fourier transform infrared spectroscopy (FTIR), proton nuclear magnetic resonance (1H‐NMR), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), and X‐ray diffraction (XRD). Increasing the molar feed ratio of LA/TEA, Tg and Mw increased. However, all copolymers were amorphous, and their Tg (12.2°C–32.5°C) were lower than that of homopolymer PDLLA. The biggest Mw was 9400 Da, which made the biodegradable polymer be potentially used as drug delivery carrier, tissue engineering material, and green finishing agent in textile industry. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011