Dry eye affects 35% of population, and it is a cause of chronic pain and discomfort. The conventional treatment with lubricants is often not sufficient in moderate to severe cases, which can lead to complications such as keratopathies, corneal opacities, ocular perforations, and visual loss. Platelet-rich plasma (PRP) eyedrops have already been used in ocular surface diseases due to their role in epithelialization and the presence of growth factors and vitamins that are similar to human tears. We intend to make a literature review of the use of platelet-rich plasma in dry eye disease, and present the results of a 13 case series, of diabetic severe dry eye patients that used this alternative treatment.
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