The authors report the case of a giant cell tumor of the frontal sinus in a 54-year-old male patient. This tumor location is rare, and this is the third case reported in the literature with radiographic documentation and histopathological confirmation. The patient underwent surgery, with curettage of frontal sinus and placement of a prosthesis. He died because a voluntary abrupt discontinuation of corticosteroids. Keywords: Giant cell tumors; Paranasal sinus; Radiology; Diagnosis.Apresentamos um caso de tumor de células gigantes do seio frontal, num paciente do sexo masculino de 54 anos de idade. É tumor de localização rara, sendo o terceiro caso relatado na literatura mundial, com documentação radiográ-fica e confirmação histopatológica. O paciente foi submetido a intervenção cirúrgica, com curetagem dos seios frontais e colocação de uma prótese, falecendo por supressão abrupta voluntária de corticosteroides. Unitermos: Tumor de células gigantes; Seios paranasais; Radiologia; Diagnóstico. AbstractResumo
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