Although TO and TA sling procedures had similar short-term results for decreasing pad use in patients with stress urinary incontinence, the transobturator approach is associated with fewer obstructive voiding complications.
A case of adenocarcinoma of the rete testis was encountered in a 36-year-old white man. The tumor fulfilled established criteria for determining origin in the rete and showed an unusual biphasic morphology with papillary adenocarcinoma mixed with a prominent component of cytologically malignant spindle cells. Immunohistochemical study demonstrated a positive reaction in the epithelium for cytokeratin and epithelial membrane antigen, and the cytoplasm of a few of the spindle cells also reacted with these antibodies. Electron microscopic study confirmed the biphasic pattern, showing epithelial gland formation and mesenchymal cells. The results indicate that this tumor is a metaplastic carcinoma of the rete testis. Recognition of this pattern of rete carcinoma may further enhance our knowledge of primary tumors at this unusual site.
We have developed the 8-(m-acetylphenyl)-2′-deoxyguanosine (mAG) scaffold for the self-assembly of supramolecules in water and for the synthesis of self-assembled dendrimers (SADs) in organic media. Previously, reported mAG assemblies showed promising characteristics for the construction of SADs. Yet, none of these SADs had large enough dendrons to reach a fractal geometry characteristic of high-generation dendrimers. Here we present the synthesis, as well as the molecular and supramolecular characterization of a fourth generation hydrophilic self-assembled hexadecameric dendrimer [mAGD4(OH)16]16•3KI (316) with a size and shape akin to globular proteins. The diameter of 316 (5.0 nm) was measured by Pulsed Field Gradient NMR and Dynamic Light Scattering experiments, which enabled the construction of a computer-generated molecular model. This SAD represents an attractive platform for biomedical applications due to its water solubility, discreteness, well defined structure, thermal stability (Tm= 68 °C), and functional core.
ResumoOs cães braquicefálicos estão predispostos às alterações dos tecidos do sistema respiratório superior, tais como: estenose das narinas prolongamento de palato mole, eversão de sáculos laríngeos e colapso laríngeo. O presente artigo descreve o caso de um cão da raça boxer, macho, com nove meses de idade que ao exame clínico, apresentou mucosas cianóticas, estenose das narinas, dispneia inspiratória, estertor respiratório e auscultação pulmonar ruidosa. Foi realizado o exame laríngeo que evidenciou o palato mole se sobrepor à epiglote em aproximadamente um centímetro. O palato mole apresentava-se espessado e com a extremidade áspera e inflamada. Devido à estenose nasal e ao prolongamento do palato foi decidido o tratamento cirúrgico, ressecção de palato mole e correção cirúrgica das narinas estenosadas.Palavras chaves: braquicefálico, cirurgia, ressecção.
AbstractBrachycephalic dogs are predisposed to alterations in the tissues of the upper respiratory system, such as: nostrils stenosis, elongated soft palate, laryngeal saccules eversion and laryngeal collapse. This article describes a male, boxer, dog, nine months of age that clinical examination showed mucosal cyanotic,
Nineteen patients with Peyronie's plaque unsuccessfully treated conservatively were considered surgical candidates. Although all patients had erections intercourse was functionally difficult to impossible for most. Only 30 per cent of the patients who underwent plaque excision and grafting became sexually functional postoperatively. Placement of penile prostheses appears to be the most secure method to rehabilitate the male patient who has become a sexual cripple secondary to Peyronie's plaque.
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