Introduction Outcome data of penile traction therapy (PTT) for the acute phase (AP) of Peyronie's disease (PD) have not been specifically studied. Aim The aim of this study was to assess the effectiveness of a penile extender device for the treatment of patients with AP of PD. Methods A total of 55 patients underwent PTT for 6 months and were compared with 41 patients with AP of PD who did not receive active treatment (“no intervention group” [NIG]). Main Outcomes Measures Pre- and posttreatment variables included degree of curvature, penile length and girth, pain by 0–10 cm visual analog scale (VAS), erectile function (EF) domain of the International Index of Erectile Function questionnaire, Erection Hardness Scale, Sexual Encounter Profile 2 question, and penile sonographic evaluation (only patients in the intervention group). Results The mean curvature decreased from 33° at baseline to 15° at 6 months and 13° at 9 months with a mean decrease 20° (P < 0.05) in the PTT group. VAS score for pain decreased from 5.5 to 2.5 after 6 months (P < 0.05). EF and erection hardness also improved significantly. The percentage of patients who were not able to achieve penetration decreased from 62% to 20% (P < 0.03). In the NIG, deformity increased significantly, stretched flaccid penile length decreased, VAS score for pain increased, and EF and erection hardness worsened. PTT was associated with the disappearance of sonographic plaques in 48% of patients. Furthermore, the need for surgery was reduced in 40% of patients who would otherwise have been candidates for surgery and simplified the complexity of the surgical procedure (from grafting to plication) in one out of every three patients. Conclusions PTT seems an effective treatment for the AP of PD in terms of pain reduction, penile curvature decrease, and improvement in sexual function.

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Heat pumps (HP) are an efficient alternative to non-electric heating systems (NEHS), being a cost-effective mean to support European building sector decarbonization. The paper studies HP and NEHS performance in residential buildings, under different climate conditions and energy tariffs, in six different European countries. Furthermore, a primary energy and environmental analysis is performed to evaluate if the use of HPs is more convenient than NEHS, based on different factors of the electric mix in each country. A specific HP model is developed considering the main physical phenomena occurring along its cycle. Open data from building, climatic and economic sources are used to feed the analysis. Ad hoc primary energy factors and greenhouse gas (GHG) emission coefficients are calculated for the selected countries. The costs and the environmental impact for both heating systems are then compared. The outcomes of the study suggest that, in highly fossil fuels dependent electricity mixes, the use of NEHS represents a more efficient decarbonization approach than HP, in spite of its higher efficiency. Additionally, the actual high price of the electric kWh hampers the use of HP in certain cases.

Stress urinary incontinence (SUI) and end-stage erectile dysfunction (ED) after radical prostatectomy (RP) can decrease a patient's quality of life (QoL). We describe a surgical technique involving scrotal incision for simultaneous dual implantation of an artificial urinary sphincter (AUS) and an inflatable penile prosthesis (IPP). Patients with moderate to severe SUI (>3 pads per day) and end-stage ED following RP were selected for dual implantation. An upper transverse scrotal incision was made, followed by bulbar urethra dissection and AUS cuff placement. Through the same incision, the corpora cavernosa was exposed, and an IPP positioned. Followed by extraperitoneal reservoirs placement and pumps introduced in the scrotum. Short-term, intra- and post-operative complications; continence status and erectile function; and patient satisfaction and QoL were recorded. A total of 32 patients underwent dual implantation. Early AUS-related complications were: AUS reservoir migration and urethral erosion. One case of distal corporal extrusion occurred. No prosthetic infection was reported. Over 96% of patients were socially the continent (≤1 pad per day) and > 95% had sufficient erections for intercourse. Limitations of the study were the small number of patients, the lack of the control group using a perineal approach for AUS placement and only a 12 months follow-up. IPP and AUS dual implantation using a single scrotal incision technique is a safe and effective option in patients with SUI and ED after RP. Further studies on larger numbers of patients are warranted.

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The present article investigates the question of building energy monitoring systems used for data collection to estimate the Heat Loss Coefficient (HLC) with existing methods, in order to determine the Thermal Envelope Performance (TEP) of a building. The data requirements of HLC estimation methods are related to commonly used methods for fault detection, calibration, and supervision of energy monitoring systems in buildings. Based on an extended review of experimental tests to estimate the HLC undertaken since 1978, qualitative and quantitative analyses of the Monitoring and Controlling System (MCS) specifications have been carried out. The results show that no Fault Detection and Diagnosis (FDD) methods have been implemented in the reviewed literature. Furthermore, it was not possible to identify a trend of technology type used in sensors, hardware, software, and communication protocols, because a high percentage of the reviewed experimental tests do not specify the model, technical characteristics, or selection criteria of the implemented MCSs. Although most actual Building Automation Systems (BAS) may measure the required parameters, further research is still needed to ensure that these data are accurate enough to rigorously apply HLC estimation methods.

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