Substitution is still a threat to the failure of ARV therapy so that no matter how small it must be noted and monitored in ARV therapy. The aims was analysis risk factor substitution ARV first line in therapy ARV. This study was an analytic longitudinal study with retrospective secondary data analysis in a cohort of patients receiving ARV therapy at the District General Hospital of Buleleng District for the period of 2006-2015 and secondary data from medical records of PLHA patients receiving ART. Result in this study that the percentage of first-line ARV substitution events is 9.88% (119/1204) who received ARV therapy for the past 11 years. Risk factors that increase the risk of substitution in ARV therapy patients are zidovudine (aOR 4.29 CI 1.31 -2.65 p 0.01), nevirapine (aOR1.86 CI 2.15 - 8.59 p 0.01) and functional working status (aOR 1.46 CI 1.13 - 1.98 p 0.01).
Daun sirsak (Annona muricata L.) diperkirakan memiliki kemampuan sebagai insektisida nabati untuk mengendalikan nyamuk Aedes aegypti penyebab Demam Berdarah Dengue (DBD). Bahan aktif yang terkandung dalam ekstrak daun sirsak yaitu saponin, flavonoid, tanin, dan alkaloid yang mempunyai kemmapuan untuk membunuh larva nyamuk Aedes aegypti. Penelitian ini bertujuan untuk menganalisis efektivitas ekstrak daun sirsak dalam berbagai konsentrasi yaitu 0%, 20%, 40%, dan 60%. Penelitian ini merupakan jenis eksperimen dengan menggunakan desain rancangan acak lengakap (RAL). Hasil penelitian dianalisa dengan uji Anava satu arah. Hasil peneilitian menunjukkan bahwa terdapat pengaruh esktrak daun sirsak terhadap jentik nyamuk Aedes aegypti dengan nilai kurang dari 0,05 (p<0,05). Analisis perbandingan (p=0,0001). Penggunaan larvasida ekstrak daun sirsak lebih efektif dalam menekan jumlah jentik nyamuk dengan konsentrasi 60%. Kata kunci: Efektivitas,daun sirsak, Aedes aegypti.
ABSTRAK Latar Belakang Penyakit menular yang selalu memberikan dampak tidak hanya kesehatan tetapi social dan ekomoni adalha HIV/AIDS.Tujuan untuk mendeskripsikan kondisi klinis dan dmeografi pasien yang menerima terapi ARV.MetodePenelitian deskriptif dengan pendekatan secara kohort retrospektifmenggunakan data sekunder dari register kohort ARV dari tahun 2005-2015 (11 tahun terapi ARV). Analisis yang digunakan adalah analisis univariat menggunakan SPSS versi 17.Hasil Karakteristik klinis dan demografi pada odha yang menerima terapi ARV yaitu 45,32% dalam kondisi ambulatory, 75.42% mendapatkan regimen NNRTI jenis zidovudine, 75.82 % mendapatkan terapi regimen NRTI nevirapine, 79.66% pada kondisi stadium 3 dan 4, dengan klasifikasi umur produktif (< 40 tahun sebanyak 82.05%, sebagian besar berjenis kelamin laki-laki 62.96%, dan memiliki pengawas minum obat (PMO) sebesar 68.25%. Proporsi kematian sebesar 9.3 % (112 orang), LTFU (loss to follow up) 18.52% (223 orang), subsitusi regimen lini satu 9.88% (119 orang),rujuk keluar 1.83% (22 orang) dan yang masih dalam pengobatan sebesar 69.93% (842).Kesimpulan Pasien yang mengalami LTFU terbagi dalam beberapa kondisi yaitu LTFU dalam kondisi meninggal 3.07% (37 orang), LTFU dalam kondisi hidup 0.5% (6 orang), dan LTFU yang tidak diketahui kondisinya sebesar 14.95% (180 orang).Saran Monitoring dan evaluasi pada program pengobatan dilakukan secara berkelanjutan untuk meningkatkan konsistensi terapi yang dilakukan. Kata Kunci : Karakteristik, Terapi, HIV/AIDS
Increased broiler production in Bogor Regency leads to the continuous development of traditional chicken collecting facilities and slaughterhouse (CCFS), especially in Bogor City. Pondok Rumput area, located in Kebon Pedes Village, as one of CCFS centers. Pondok Rumput CCFS was first established in 1971. There are currently 25 CCFS in Pondok Rumput. The CCFS in this area are located in densely populated residential area. The CCFS, are located in the middle of the residential area leads to various problems, one of which is environmental pollution.The Study aimed to identify the factors determining the sustainability status of CCFS in Pondok Rumput area, in Tanah Sareal Subdistric, Bogor City. The types of data collected included primary and secondary data. The data analysis used by Multi Dimensional Scalling (MDS) analysis (by using Rapfish software) and prospective analysis. Partial analysis of each dimension concerning the sustainability status of chicken collecting facilities and slaughterhouse in Pondok Rumput showed that ecological dimension were not unsustainable with a value of 24.66. The key attributes were having business license, conformity to slaughtering regulations, entrepreneurs’ attitudes towards relocation, and business feasibility.
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