To determine whether transplacental transmission could explain overwintering of bluetongue virus in the United Kingdom, we studied calves born to dams naturally infected during pregnancy in 2007–08. Approximately 33% were infected transplacentally; some had compromised health. In all infected calves, viral load decreased after birth; no evidence of persistent infection was found.
Background: Emphasis is currently placed on the importance of employee and student wellness initiatives. The aim was to assess staff and student health status at the Faculty of Medicine and Health Sciences (FMHS), Stellenbosch University (SU), and to conduct a wellness needs assessment. Methods: Online, self-administered questionnaires were used to collect data concerning staff and students. Additionally, students' anthropometric and biochemical parameters were assessed. Summary statistics, correlation coefficients and appropriate analysis of variance were used for data analyses. Results: Data were obtained from staff (survey: n = 300) and students (screening: n = 536; survey: n = 330). Some 58% (n = 174) of staff had a self-reported BMI of ≥ 25 kg/m 2 whilst mean screening values for all variables fell within normal reference ranges for students. In all, 78% (n = 232) of staff reported to exercise < 150 min/week and 28% (n = 91) of students were sedentary for > 8 h/day; 63% (n = 188) of staff expressed the need to make better food choices, 17% (n = 55) of students were aware of the need to change but experienced reluctance, and both staff and students felt dietary assistance would be beneficial (43% vs. 46%). In addition, 79% of staff (n = 208) and 42% of students (n = 138) reported being under constant pressure. Conclusion: Much can be done to improve the health and well-being of both staff and students at the FMHS, SU. Wellness is a multifactorial concept; as such, health-promotional strategies for classrooms and workplaces should consider all factors in order to provide a holistic approach and potentially identify those who are at risk of a sub-optimal wellness status.Keywords: health sciences, health screening, online survey, staff and student wellness IntroductionThe World Health Organization (WHO) defines wellness as not only the absence of illness but a state of complete physical, mental and social well-being.1 Wellness is a multifaceted concept that incorporates seven dimensions, namely social, emotional, physical, intellectual, spiritual, environmental and occupational wellness.2 These aspects are believed to be a worthy focus for employee and student wellness programmes, as they exist as a holistic model wherein the diverse dimensions are interdependent.1 It is important to be able to identify these dimensions and implement a programme that addresses these within an organisation. From the standpoint of an employee, not only is each dimension of wellness important, but the ability to balance these dimensions is fundamental.3 Employees of an organisation should have access to wellness programmes, along with incentives that encourage participation. This change in behaviour can be beneficial in improving organisational culture, 4 decreasing absenteeism, reducing medical costs and improving well-being of employees. Similarly, many studies have been conducted worldwide emphasising the unhealthy behaviour and lifestyles of university students. [6][7][8][9][10][11][12][13][14][15][16] Behaviours and lifestyle...
Bradford Scholars -how to deposit your paper Overview Copyright check• Check if your publisher allows submission to a repository.• Use the Sherpa RoMEO database if you are not sure about your publisher's position or email openaccess@bradford.ac.uk.
Objectives: In this histological study, we analysed the use of a new tulip-shaped self-expandable catheter fixed to the fibre for endovenous laser treatment (ELT) in an animal
Idiopathic pulmonary fibrosis (IPF) affects 34/100000 people per year. Currently there is no cure for IPF, partially because the etiology remains unknown. IPF is believed to develop through three phases: inflammation, alveolar epithelial damage, and fibroblast response resulting in excess matrix. TGF‐b is known to play a critical role in the development of fibrosis in IPF as well as other fibrotic diseases. We have employed the use of a bleomycin‐induced model of pulmonary fibrosis to evaluate a pan‐ TGF‐b neutralizing antibody (1D11) as a potential therapeutic. Although bleomycin treatment induces several pro‐inflammatory and pro‐fibrotic responses, TGF‐b is upregulated and modulation of TGF‐b has been suggested to result in decreased fibrosis. Following bleomycin administration, mice developed fibrosis, which was abrogated by 1D11 treatments. In addition, flexiVent analysis revealed significant changes in functional parameters, which 1D11 treatments improved. In initial studies, direct 1D11 administrations prevented the development of alveolar/perivascular inflammation as well as fibrotic lesions. Furthermore, 1D11 treatments prevented reduction of functional parameters, most notably elastance. These studies have demonstrated functional and histologic improvement with 1D11 and provide support for the utilization of therapeutic TGF‐b neutralizing antibodies for the treatment of IPF.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.