RESUMO -O câncer é considerado um importante problema de saúde pública. A etiologia é multifatorial, e considera-se que existe uma correlação entre fatores internos e externos possivelmente associados ao desenvolvimento da doença. A exposição ambiental/ocupacional a agentes químicos carcinogênicos como alguns agrotóxicos, derivados do benzeno e o thinner, é uma das condições possivelmente associadas ao desenvolvimento do câncer. Portanto, objetivou-se apresentar o perfil epidemiológico dos pacientes com cânceres hematológicos, em tratamento na região oeste de Santa Catarina, analisando os cânceres prevalentes e o contato com substâncias
The aim of this study was to analyze the association between chronic exposure to pesticides and the development of hematological cancers in a region with intense agricultural activity. This is a hospital-based case-control study. Socioeconomic, demographic, occupational and health-related aspects of patients were investigated. The univariate odds ratio (OR) of cases was verified using logistic regression analysis. In the multivariate analysis, the relevant variables in the model were maintained (p = 0.05). There was a predominance of males in the case (54.0%) and control (53.0%) groups. The mean age was 58.8 ± 14.5 years in the case group and 55.6 ± 12.9 years in the control group. It was found that 38.7% of the cases were farmers, and that contact for more than five years with pesticides increases the chances of developing hematological cancers by 2.19 times (OR = 2.19; 95% CI 1, 19 - 4.06). It was also found that the higher the family income, the lower the chances of these neoplasms to appear (OR = 0.26; 95% CI 0.11 - 0.65). In addition, patients who did not have a family history of cancer were 96% less likely (OR = 0.04; 95% CI 0.02 - 0.08) to develop the disease. Chronic exposure to pesticides, family history of cancer and socioeconomic status are associated with greater chances of developing hematological neoplasms. Rural workers exposed to these substances for periods of more than five years are more vulnerable.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
334 Leonard St
Brooklyn, NY 11211
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.