SUMMARY -Migraine and tension type headache are the most common disabling primary headache disorders. Epidemiological studies have documented their high prevalence and high socioeconomic and personal impacts. According to recent data, migraine ranks as the third most prevalent disorder and seventh-highest specifi c cause of disability worldwide. Tension-type headache has lifetime prevalence in the general population ranging between 30% and 78% in diff erent studies. According to the International Classifi cation of Headache Disorders, 3 rd edition, there also are many other headaches but their incidence in general population is lower than the previously mentioned headaches. Trigeminal nerve and upper cervical segments (C1-C3) are included in pain control of the head region and often evaluated in headache studies in order to improve diff erential diagnosis and headache treatment. In our study, we evaluated the potential role of electromyographic (EMG) blink refl ex in establishing diagnosis of headache and evaluation of trigeminal nerve dysfunction as the possible underlying pathomorphological headache mechanism. Our study included 60 patients with diff erent types of primary headaches and 30 control subjects. Statistical analysis was performed by use of χ 2 -test and statistical signifi cance was set at p<0.001. Study results showed that patients with trigeminal dysfunction in EMG blink refl ex had a 5.6-fold higher risk of developing headache in comparison to subjects with normal EMG blink refl ex fi nding.
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