The communication attitude (ACO) of nurses can significantly influence patient health outcomes. This work aims to evaluate predictor variables of communication attitude (emotional intelligence and social skills) in nurses and nursing students separately by comparing linear and non-linear methodologies. Two samples participated in this study: 312 nursing professionals and 1369 nursing students. In total, 75.60% of the professionals and 83.80% of the students were women. After signing the informed consent form, their emotional intelligence (TMMS-24), social skills (IHS) and ACO (ACO) were assessed. It was found that ACO through linear regression models in professionals was predicted by emotional repair and, in students, by attention and emotional repair, as well as by low exposure to new situations, low social skills in the academic or work area and high empathy. Overall, the comparative qualitative models show how the combination of different skills related to emotional intelligence and social skills lead to high levels of ACO. Conversely, their low levels result in an absence of ACO. Our results highlight the importance of emotional intelligence, especially emotional repair and empathy, as well as the need to consider ways to encourage the learning of these skills in a formal way.