The authors describe the case of a young female patient with primary amenorrhea and normal secondary sexual characteristics. The diagnostic investigation demonstrated the occurrence of Mayer-Rokitansky-Kuster-Hauser's syndrome. Keywords: Paramesonephric (Müllerian) ducts; Abnormalities.Os autores descrevem o caso de uma paciente jovem com amenorreia primária e caracteres sexuais secundários normais. A investigação diagnóstica constatou a ocorrência da síndrome de Mayer-Rokitansky-Kuster-Hauser. Unitermos: Ductos paramesonéfricos; Anormalidades. AbstractResumo

Patient: Female, 46Final Diagnosis: Plasmablastic lymphomaSymptoms: Fecal incontinenceMedication: ChemotherapyClinical Procedure: Anal canal biopsySpecialty: Internal medicine • Oncology • RadiologyObjective:Unusual clinical courseBackground:The advent of antiretroviral therapy increased the life expectancy of human immunodeficiency virus (HIV)-positive patients and, consequently, the morbidity and mortality due to neoplasms. Plasmablastic lymphoma is one such neoplasm that generally presents with involvement of the oral cavity; cases of extra-oral involvement are rare.Case Report:We report a case of plasmablastic lymphoma in a 46-year-old woman for whom the initial clinical manifestation was a painless perineal tumor accompanied by fecal incontinence.Conclusions:The possibility of this neoplasm should be considered in patients with HIV/acquired immune deficiency syndrome (HIV/AIDS) because its early diagnosis is essential so that the start of the treatment is not delayed.

Ischemic strokes secondary to occlusion of large vessels have been described in patients with COVID-19. Also, venous thrombosis and pulmonary thromboembolism have been related to the disease. Vascular occlusion may be associated with a prothrombotic state due to COVID-19-related coagulopathy and endotheliopathy. Intracranial hemorrhagic lesions can additionally be seen in these patients. The causative mechanism of hemorrhage could be associated with anticoagulant therapy or factors such as coagulopathy and endotheliopathy. We report on cases of ischemic, thrombotic, and hemorrhagic complications in six patients diagnosed with SARS-CoV-2 infection. Chest computed tomography (CT) showed typical SARS-CoV-2 pneumonia findings in all the cases, which were all confirmed by either serology or reverse transcription polymerase chain reaction (RT-PCR) tests. Case 1A 29-year-old woman who was 5 weeks pregnant, previously healthy, was diagnosed with COVID-19 12 days before hospital admission, when both immunoglobulins (IgM and IgG) were positive. While in home quarantine, the patient manifested sudden right hemiplegia and aphasia 48 hours before hospital admission. Upon arrival to the emergency room, she was disoriented and had right hemiplegia.