Aarskog–Scott syndrome is a genetically and clinically heterogeneous rare condition caused by a pathogenic variant in the FGD1 gene. A systematic review was carried out to analyse the prevalence of clinical manifestations found in patients, as well as to evaluate the genotype-phenotype correlation. The results obtained show that clinical findings of the craniofacial, orthopaedic, and genitourinary tract correspond to the highest scores of prevalence. The authors reclassified the primary, secondary, and additional criteria based on their prevalence. Furthermore, it was possible to observe, in accordance with previous reports, that the reported phenotypes do not present a direct relation to the underlying genotypes.

Background Inequitable representation in journal editorial boards may impact women's career progression across surgical, anesthesia, and obstetric (SAO) specialties. However, data from Latin America are lacking. We evaluated women's representation on editorial boards of Latin America SAO journals in 2021. Methods We conducted a cross-sectional analysis, retrieving journals through Scimago Journal and Country Rank 2020. Journals were included if active, focused on SAO topics, and publicly provided information on editorial board staff. Editorial board member names and positions were extracted from journals' websites. Members were classified into senior (e.g., editor-in-chief), academic (e.g., reviewer), and non-academic roles (e.g., administrative office). Women's representation was predicted from first names using Genderize.io. The number of women SAO physicians per country was obtained from articles and governmental reports. Results We included 19 of 25 identified journals and analyzed 1,318 names. Three anesthesiology, seven obstetric, and nine surgical journals represented five Latin American countries. Women held 17% (224/1,318) of board positions [p \ 0.0001; 95% CI(0.14, 0.19)]. Women held fewer academic roles (14.3%, 155/1,084) compared to senior [28.9%, 64/221 (p \ 0.001)] and non-academic roles [38.4%, 5/13 (p = 0.042)]. Surgical journals had fewer women (7.7%, 58/752) compared to anesthesia [25.5%, 52/204 (p = 0.006)] and obstetrics [31.5%, 114/362 (p \ 0.001)]. Women's proportion on editorial boards increased according to the number of women SAO physicians per country (p \ 0.001). Conclusions Our study assessed the composition of editorial boards from Latin America SAO journals and demonstrated that women remain underrepresented. Our findings highlight the need for regional strategies to advance women's careers across SAO specialties.

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With improved resources for the prevention, diagnosis, and treatment of infective endocarditis (IE), significant changes in the characteristics of the disease have been reported over time. If, on the one hand, the prevalence of IE due to rheumatic valve disease has decreased, on the other, there has been an increase in IE related to degenerative valve disease in older adults, valve replacement surgery, the implantation of intracardiac devices, and the use of injectables and hemodialysis.Coincidentally, IE cases due to Staphylococcus spp. have surpassed those of Streptococcus spp., and cases due to atypical microorganisms have also increased. 1,2 This microbiological change is attributed to medical progress and the resulting increase in invasive procedures. 3,4 Despite efforts to the contrary, IE is still considered a condition with persistently high morbimortality,

Os autoresEste trabalho está licenciado com uma Licença Creative Commons -Atribuição-NãoComercial-SemDerivações 4.0 Internacional.O conteúdo abordado nos artigos, seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores.