Sulfonyl
fluorides are valuable synthetic motifs for a variety
of applications, among which sulfur(VI) fluoride exchange-based “click
chemistry” is currently the most prominent. Consequently, the
development of novel and efficient synthetic methods to access these
functional groups is of great interest. Herein, we report a mild and
environmentally benign electrochemical approach to prepare sulfonyl
fluorides using thiols or disulfides, as widely available starting
materials, in combination with KF, as an inexpensive, abundant and
safe fluoride source. No additional oxidants nor additional catalysts
are required and, due to mild reaction conditions, the reaction displays
a broad substrate scope, including a variety of alkyl, benzyl, aryl
and heteroaryl thiols or disulfides.
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