The cost-effectiveness ratios for insulin glargine use for type 1 and 2 diabetes provide evidence for its adoption from a Canadian healthcare payer perspective.
Key MessagesIn clinical trials, Gla-300 had similar glycated hemoglobin (A1C) reduction and a lower risk of hypoglycemia than Gla-100 in patients with type 1 diabetes (T1D) and type 2 diabetes (T2D). In a real-world clinical setting, insulin-naïve patients with T2D initiating Gla-300 or Gla-100 had similar A1C reduction and weight change.Patients with T1D or T2D switching to Gla-300 had significant reductions in A1C with no change in weight or insulin dose.
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