Background:One of the nursing activities in the hospital is the scheduling that requires a nursing specific knowledge of pharmacology to avoid potential drug interactions (PDIs). Objective: To analyze the characteristics of the medication schedule established by nurses and to identify PDIs. Methods: Retrospective cross-sectional study developed in a specialized adolescent health unit at a public hospital in Rio de Janeiro, Brazil. The sample consisted of 79 prescriptions based on a sample size calculated for a power of 0.8. Odds ratios were calculated, and a significance level of 5% was considered. The drug pairs that were scheduled at the same time were tested using the Micromedex software and analyzed using the statistical software R. Results: Among the prescriptions, those containing more than 5 drugs had two times the odds (OR: 2.5) of being associated with PDIs. Phenytoin was involved in 4 events. Suggested nursing care actions for PDIs include observing signs and symptoms, monitoring the therapeutic response and possible adverse reactions, and intervening according to the specific complications. Conclusion: It study highlighted aspects related to medication scheduling which is a routine nursing activity, and when it is done correctly can avoid PDIs and Drug Interactions promoting safety patient.
The aim of this study was to assess the knowledge of nursing teams that care for hospitalized adolescents undergoing glucocorticoid infusion and to develop an educational protocol for nursing care during pulse therapy. This descriptive, exploratory study with a qualitative approach was developed in a unit specializing in adolescent health at a university hospital in the state of Rio de Janeiro, Brazil. The instrument used for data collection was a semistructured interview conducted in a private room on the unit. The main results indicated that nursing knowledge was focused on the need to evaluate hemodynamic parameters, the care required during infusion therapy, and the complications resulting from the treatment. Educational material was developed to support a holistic view of the adolescent undergoing pulse therapy. Based on information received from the nursing team, it was determined that, although the team performed all the technical aspects of the infusion procedure well, their care did not address specific needs of the adolescent patient, guidance on infection prevention, or hemodynamic evaluation. After evaluating the nursing team's experience, knowledge, and perceptions, the researchers were able to develop appropriate protocols to guide care for hospitalized adolescents undergoing glucocorticoid infusion therapy.
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