Studies published between the beginning of 2013 and May 2015 on the neuropsychological functioning of patients with anorexia nervosa compared with healthy participants framed in the context of the Research Domain Criteria matrix identifies evidence for functional differences in three domains: Negative Valance Systems-negative attentional biases and lack of neural responsivity to hunger; Cognitive Systems-limited congruence between clinical and cognitive performance, poorer non-verbal than verbal performance, altered attentional styles to disorder related stimuli, perceptual processing impairment in discriminating body images, weaknesses in central coherence, set shifting weaknesses at low weight status, decision-making weaknesses, and greater neural resources required for working memory; Systems for Social Processes-patients appear to have a different attentional response to faces, and perception and understanding of self and others. Hence, there is evidence to suggest that patients with anorexia nervosa have a specific neuropsychological performance style across tasks in three domains of functioning. Some current controversies and areas for future development are identified.
1. Records used to compile the Contemporary Comparisons of 57 Friesian, 8 English Ayrshire and 11 Scottish Ayrshire A.I. bulls, each with at least 100 ‘effective daughters’ were analysed.2. For each bull, the herd-years were divided into three equal groups on the basis of the average heifer yield of both daughters and contemporaries (high-, medium-, and low-producing herd-years) and three independent Contemporary Comparisons were calculated for each bull, one at each of the three yield levels.3. In the data from England and Wales, the mean Contemporary Comparison declined with increasing mean level of production. This decline was such as to imply that some 20% of the differences in production between herds were genetic in origin. A possible explanation lies in the gradual change from Dairy Shorthorn to Friesian and Ayrshire which has taken place in England and Wales, but not in Scotland, during the last 15 years.4. The variance within progeny groups within herd-years increased from the low level to the high but the coefficient of variation decreased slightly. The variance between sires also increased with the mean level of production but almost exactly in parallel with that within sires so that the heritability and consequently the accuracy of the progeny test for milk yield was effectively the same at all production levels.5. The correlation between the true breeding values of the bulls at the different levels was very close to one.6. From these results it is concluded that there is no need to provide special strains within breeds to suit particular management levels or to concentrate progeny testing in the higher-producing herds and that daughter records from all herds, irrespective of level of production, can be used with equal confidence.
Background Chronic pain is common after spinal cord injury (SCI) and dedicated SCI cognitive behavioural therapy pain management programmes (CBT‐PMPs) have a growing evidence base to support their uptake clinically. The development of internet‐delivered treatment options may overcome barriers to the access and uptake of centre‐based programmes. This study examines such an approach on quality of lie (QoL), pain, mood and sleep. Methods Adults with SCI pain (>3 months) were recruited and randomly assigned to the intervention or control group. The intervention comprised a six module CBT‐PMP delivered once weekly. A blinded assessor determined changes in self‐reported outcome measures post‐intervention and at 3 months. Linear mixed models and effect sizes based on changes between groups were reported. Significance was set p < 0.05. Results The recruitment rate was 32% (intervention n = 35, control n = 34), and the drop‐out rate at 3 months was 26%. On average, participants accessed three (SD 2.1) of six modules. While no difference in QoL was reported, a significant group*time interaction was found for NRS of current pain (χ2 = 8.22, p = 0.016), worst pain (χ2 = 11.20, p = 0.004), and Brief Pain Inventory (interference) (χ2 = 6.924, p = 0.031). Moderate to large effect sizes favouring the intervention were demonstrated at each time point for the pain metrics (Cohen's d: 0.38–0.84). At 3‐month follow‐up, 48% of the intervention group rated themselves improved or very much improved (p < 0.05). Conclusions This study demonstrates the potential of an internet‐delivered SCI specific CBT‐PMP in reporting significant statistical and clinical benefit in pain intensity and interference. Strategies to improve engagement are needed.
Link to this article: http://journals.cambridge.org/abstract_S0003356100038599 How to cite this article: L. K. O'Connor and M. B. Willis (1967). The effect of articial insemination on the breed structure of British Friesian cattle.
1. A field investigation to estimate the mean weight and chest girth of unserved Friesian, Ayrshire and Dairy Shorthorn heifers of between 3 and 24 months of age was carried out.2. Data from 1,620 Friesians, 725 Ayrshires and 455 Dairy Shorthorns in the North of England were obtained, with a mobile weighbridge and a. spring-loaded steel tape in the winter 1958–59.3. It was found that on average the Friesians were heavier and had a greater chest girth than the Ayrshires and Dairy Shorthorns, which did not differ significantly.4. These heifers were apparently reared on planes of nutrition which, judged by conventional feeding standards, may be described as ‘low’.5. After eliminating the linear effect of age by covariance analysis, highly significant differences between herds and between sires in weight and chest girth were found.6. The investigation demonstrated the feasibility and value of collecting field data on body size.
SummaryA study was made of the effect of various sampling intervals on the accuracy of estimating lactation milk yield, fat yield, solids-not-fat (S.N.F) yield, fat percentage and S.N.F. percentage. The basic data consisited of daily milk, fat and S.N.F. yields for eighteen lactations made by twelve Dairy Shorthorn cows. Estimates of the lactation yields and quality were obtained using sampling intervals of 7, 14, 28, 42, 56 and 63 days, and were expressed as differences from the actual values. Only in the case of milk yield was there any effective bias in the estimates. This bias increased with increasing sampling interval.The distributions of differences between estimated and actual values are presented. The error of estimation increased with increasing sampling interval. Keeping in mind the comparatively small-sized sample used in the investigation, the results are discussed in the light of the purposes for which records are kept.
The Milk Marketing Board's 23 artificial insemination (AI) centres which provide service in much of England and Wales are grouped into five geographical areas (Figure 1). Analyses of trials on commercial farms to study the effects of crossing Charolais bulls with dairy cows (Edwards et al. 1966), revealed significant differences between these areas in both gestation length and birth weight of crossbred calves. However, the Charolais bulls used in the trials were divided into five teams, each of three bulls, and each team was used only in a single area. Consequently, bull teams and areas were confounded. The purpose of the experiment reported here was to estimate the differences between areas in gestation length and birth weight independent of sire.
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