To analyze the relationship between anxiety and depression and quality of life in chronic renal failure patients on hemodialysis. This is a correlational study with a cross-sectional, quantitative approach, conducted with 100 kidney patients under treatment at a Renal Replacement Therapy Unit in the state of São Paulo. Data were collected using a sociodemographic questionnaire, Hospital Anxiety and Depression Scale and Kidney Disease and Quality of Life Short-Form. A negative correlation was found between anxiety and depression and the quality of life domains. In addition, the average scores on the Kidney Disease and Quality of Life Short-Form were significantly lower in patients with anxiety and depressive symptoms. In conclusion, there is a negative correlation between depression and anxiety and the health-related quality of life of chronic renal failure patients on hemodialysis.
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