IntroductionHuman reproductive failure is defined as the inability to conceive or carry pregnancy to term. In humans this is a frequent event. It is estimated that fetal viability is achieved in no more than 30% of the spontaneous conceptions (1). In Assisted Reproductive Technologies (ART) it is well known that no more than 30% of transferred blastocysts are able to implant and initiate a pregnancy (Glukosky Cochrane 2016). The miscarriage rate (loss of clinically recognized pregnancies prior to the 20th week of gestation) in humans is around 15% (2). The reasons for this low reproductive efficiency reside mainly on the generation of a large number of abnormal
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