Background: Acute coronary syndrome was one of the most common cause for mortality and morbidity all over the world. Epicardial arterial atheroscleorosis was the main risk factor for coronary heart disease. Dyslipedemia is one of the most important risk factor for atherosclerosis and its consequences. Aims and Objectives: To study lipid profile pattern in acute coronary syndrome patients Materials and Methods: It was a retrospective study conducted between January 2017 to December 2017 at Govt Hospital MIMS Mandya. As per inclusion criteria and exclusion criteria cases are included and excluded, and a prestructured proforma was used, and data were entered. A standard serum lipid profile measures the concentration of total and high-density lipoprotein (HDL) cholesterol as well as the triglycerides.
Introduction: Organophosphate compounds are one of the most common cause of poisoning worldwide. There are emerging option for severity assessment of OP copmpound poisoning like creatine phosphokinase level. These are cheap and easily quantifiable bio marker. Study aimed to assess serum creatine phosphokinase (CPK) level in OP poisoning and to find out the correlation of serum creatine phosphokinase (CPK) level with the severity of OP poisoning Material and methods: 55 patients of acute organophosphorous poisoning admitted to medical wards and Intensive Medical Care Unit (IMCU) at Mandya Institute of Medical Science (MIMS) hospital, Mandya, during the period of July-2017 to December-2017 was taken up for study considering the inclusion and exclusion criteria's.The clinical severity was assessed and categorized according to Peradeniya Organophosphorous Poisoning scale. A brief history and detailed clinical examination was performed and patients were categorized on the basis of POP score. Level of serum cholinesterase and serum CPK were estimated at admission and CPK level was measured on day 3 and day 5. The outcome of these patients was evaluated. Results: Out of 55 patients, 63.6% were males and 36.4% were females. Majority of patients were in the age group 21-30 years. Dichlorvos was the most common compound used followed by Chlorpyrifos. 67.3% had mild, 16.4% had moderate and 16.4 had severe poisoning. Serial measurements of serum CPK levels showed significant correlation with the severity of acute OP poisoning patients. The CPK levels showed a sensitivity of 70% and a specificity of 82% with a positive predictive value of 95%. Conclusion: High serum CPK level was associated with increased risk for intermediate syndrome and increased mortality. It can be used for assessing the severity of poisoning and early intervention like putting on mechanical ventilation and preventing mortality.
Background: Poisoning is the major health problem in India. Rodenticides are the commonest poisoning in Asian countries like India. Rodenticides are the substance used to kill rats. Prognosis mainly depends on chemical content of poison.Methods: This retrospective record-based study was conducted between January 2017 to December 2017 at government hospital department of general medicine, MIMS, Mandya, Bangalore, Karnataka, India. Data regarding age, sex, marital status, occupation, type of poison, route of exposure, and outcome of poisoning and associated co-morbid conditions were collected from the hospital records and documented in the pre-structured proforma. Descriptive analysis was carried out by the mean and standard deviation for quantitative variables, frequency and proportion for categorical variables.Results: Out of 56 patients 33 (59%) were female 23 (41%) were male. Most common age group was 20 to 30 years, followed by 31 to 40 years group. Most common poison was yellow phosphorous (41%), followed by aluminium phosphide (29%). Most common complication was hepatitis (20%),followed by cardiogenic shock (9%).Total mortality was 3 (5%).Conclusions: Among rodenticides yellow phosphorous was most common consumed poison in present study. Aluminium phosphorus was most lethal poison. Even though there is no specific antidote, early symptomatic treatment is the key in reducing the mortality.
Background: Hyponatremia is one of the commonest electrolyte abnormality in clinical practice and most common cause for hospital admission among elderly patients. Causing significant mortality and morbidity. Early detection and treatment may significantly decrease mortality.
Introduction: Poisoning is one of the commonest health problems in patients who present to Emergency Department, causing significant morbidity and mortality in them. Study aims and objectives were to know the reason for poisoning, to know the relationship between poisoning and their socioeconomic status and to study morbidity and mortality of such poisoning patients Material and methods: Study was done at a tertiary care teaching hospital at MIMS, Mandya. Study was conducted between July-2017 to December 2017. Data was collected from all the poisoning cases admitted during this period to the emergency ward and medical wards. Demographics, etiological and clinical profile were studied. Results: Out of 260 patients, there were 120 (46%) males and 140 (54%) females. Out of 260 patients 209 (80%) patients belong to hindu religion. Out of all patients 160 (61.5%) were from rural area and 100 (39.5%) were from urban area. Age of the patients ranged from 17 to 70 years. Vomiting and pain abdomen was the predominant symptom [(n=93 (35.8%)], followed by giddiness (8%) and breathlessness (7.3%). Drugs of different class (34.6%) was the most common poison followed by Organophosphate compounds (15%) followed by Rat killer (10.4%) poison. Mortality was found to be 6.2% and was mainly due to organophosphate compounds. Conclusion: Poisoning was more common in young female patients, so they should be emotionally supported in stressful circumstances, poisoning was more common in rural areas because of there occupation like agriculture and easy availability of compounds. Mortality was higher in case of organophosphate poisoning. Early care in tertiary centre may help to reduce mortality in India.
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