Aims:
1. To evaluate the prognostic value of SpO2 in cancer patients 2. To correlate between daily SpO2 values and tumor response to radiation.
Background:
Tumor hypoxia is an important prognostic factor in Oncology. It plays an important role in tumorogenesis, radiation resistance and tumor progression. Many invasive and in-vitro methods are available to assess the hypo-oxygenated status of tumors.
Objective:
We evaluated if SpO2 values measured from pulse oximetry could be used as an adjunct prognostic and predictive factor in oncology patients.
Methods:
Ten consecutive patients with locally advanced, non-metastatic disease were evaluated. Daily SpO2 measurements throughout the treatment and weekly haemoglobin values were noted. All patients received radical intent radiation therapy. Patients were categorised into two groups: poor SpO2 (<97mmHg) and better SpO2 (≥98mmHg).
Results:
Tumour response was higher in patients with better SpO2 (≥98mmHg). Patients with poor SpO2 (<97mmHg) presented with bulkier disease at diagnosis.
Conclusion:
Role of SpO2 as a prognostic and predictive factor should be explored further with in vitro and pH studies.
The advent of graph theory has played a prominent role in wide variety of engineering applications. Minimization of crossing numbers in graphs optimizes its use in many applications. In this paper, we establish the necessary and sufficient condition for SemiImage neighborhood block graph to have crossing number 3. We also prove that the SemiImage neighborhood block graph NB I (G) of a graph never has crossing numbers k, where 1 ≤ k ≤ 6.
In present scenario cases of infertility arise abundantly which is a serious problem among the present generation as it affects the person mentally hence can deteriorate life. There are various etiological factors related to male infertility. In Ayurveda the quality of Shukra is mentioned by various Acharya to produce a healthy progeny. But Shukra Dushti can lead to differently abled or no progeny. There are various types of Shukra Dushti mentioned by Acharya Sushrut, Ksheena -Shukra is one of them. Aim: To compare the efficacy of Virechana Karma followed by Ashwattha Churna and Ashwattha Churna alone in Ksheena Shukra (oligozoospermia). Objective: To assess the efficacy of Virechana Karma followed by Ashwattha Churna in Ksheena Shukra and to assess the efficacy of Ashwattha Churna alone in Ksheena Shukra and to detect increase in sperm count. Methods: It is open label, randomized, interventional and comparative study. Group A - In this group Virechana Karma followed by Ashwattha Churna was given. Group B - In this group Ashwattha Churna was given. Result: Group A (Virechana Karma followed by Ashwattha Churna) there was an increase of 55% in sperm count, increase of 11.6% in sperm motility, relief in Maithuna Ashakti is 50%, relief in Medra Vrishna Vedana is 32%, and relief in Chiraat Prashek is 32%. Conclusion: Both group shows statistically significant results in parameters i.e., Maithuna Ashakti, Medra Vrishna Vedana, Chiraat Prashek, sperm count, motility.
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