In our opinion, intraoperative air testing of colorectal anastomosis is a good method for prevention of anastomotic dehiscence.
The influence of soybean seed coat color and genotype on antioxidant capacity, phenolic content and isoflavone profile was investigated. Isoflavone content and composition of 21 seed samples-yellow, green, brown, black and rarely mentioned ocher and reddish, were determined by high-performance liquid chromatographic analysis. Antioxidant capacity and total phenolic content (TPC) were evaluated spectrophotometrically. Significant correlation between total isoflavone content and total genisteins was established in all colored groups. Total isoflavone content was in the range from 2.11 mg/g in a green wrinkled sample to 5.24 mg/g in yellow seed. It was found that black genotypes had the highest TPC and antioxidant capacity, which were significantly different (p<0.05) from other colored soybeans. The obtained interconnections among analyzed isoflavones can be used as a model for estimation of their specific content.
The aim of this work was to investigate possible protective effect of celery juice in doxorubicin treatment. The following biochemical parameters were determined: content of reduced glutathione, activities of catalase, xanthine oxidase, glutathione peroxidase, peroxidase, and lipid peroxidation intensity in liver homogenate and blood hemolysate. We examined influence of diluted pure celery leaves and roots juices and their combinations with doxorubicine on analyzed biochemical parameters. Celery roots and leaves juices influenced the examined biochemical parameters and showed protective effects when applied with doxorubicine.
Acute effects of different extracts of mistletoe stem (Viscum album) were investigated on values of arterial blood pressure in Wistar rats. Arterial blood pressure was registered by direct method in the left carotid artery and the investigated extracts (total ethanol, ether and ethyl acetate) of mistletoe stem were administered into the right jugular vein. The total ethanol extract exhibited the best effect even on the lowest applied concentration (3.33 x 10(-5) mg kg(-1)) and significantly decreased the blood pressure after applied concentration 1.00 x 10(-3) mg kg(-1). On the contrary, the ether and ethyl acetate extracts exhibited notable activity only by higher administered doses. Atropine as a nonselective blocker of muscarinic receptors reduced the hypotensive effects of ethanol extract of mistletoe. Hexocycline, a selective blocker of muscarine receptors, significantly raised blood pressure and decreased the hypotensive effect of ethanol extract of mistletoe on arterial blood pressure in rats.
Autologous blood transfusion is a very effective method for reducing consumption of allogenic blood and thus, indirectly for reducing all complications related to allogenic blood transfusion. There is also a positive influence on postoperative recovery after total knee replacement surgery due to the reduction of hospital stay, and indirectly on the reduction of hospital costs.
Background/Aim. Catheter-related infections are a significant morbidity and mortality cause in patients on hemodialysis. The objective of this study was to determine the incidence, to analyze risk factors and to identify etiological causes of catheter-related infections in these patients. Methods. The study was carried out at the Clinic for Nephrology and Clinical Immunology of the Clinical Centre of Vojvodina, from August, 2012 to May, 2015. One hundred and thirteen patients on chronic hemodialysis participated in the study. The risk factors of catheterrelated infections in the infected patients were to those in the control group, as follows: demographic and laboratory parameters, co-morbidities and the use of immunosuppressive therapy, the length of hemodialysis treatment, urgent catheter placement, the position and placement difficulties, the number of insertions and catheter maneuvering, the existence of permanent vascular access in maturation or without a vascular access in the course of catheter positioning, catheter life, surgical procedures (≤ 30 days from catheter placing), the length of hospitalization and isolated infection causes. Results. One hundred and Key words: renal dialysis; catheter-related infections; risk factors.Apstrakt Uvod/Cilj. Infekcije povezane sa kateterom i dalje predstavljaju značajan uzrok morbiditeta i mortaliteta kod bolesnika na hemodijalizi. Cilj ovog ispitivanja je bio da se utvrdi incidencija, analiziraju faktori rizika i identifikuju etiološki uzročnici kateter infekcija kod ovih bolesnika. Metode. Ispitivanje je sprovedeno na Klinici za nefrologiju i kliničku imunologiju Kliničkog centra Vojvodine u periodu od avgusta 2012. do maja 2015. godine. Ispitivanjem je bilo obuhvaćeno 113 bolesnika lečenih hroničnim hemodijalizama. Upoređivani su faktori rizika od infekcija povezanih sa kateterom kod bolesnika sa dokazanom infekcijom u odnosu na kontrolnu grupu. Analizirani su demografski i laboratorijski parametri, komorbiditeti i upotreba imunosupresivne terapije, dužina dijaliziranja, urgent-no plasiranje, pozicija i otežano plasiranje katetera, broj mesta insercije i manipulacija kateterom, postojanje trajnog vaskularnog pristupa u maturaciji ili bez vaskularnog pristupa tokom plasiranja katetera, dužina trajanja katetera, hiruške intervencije (≤ 30 dana od plasiranog katetera), dužina hospitalizacije i izolovani uzročnici infekcija. Rezultati. Kod 113 bolesnika plasirano je 197 katetera, od kojih su 182 bila privremena. Ukupni broj dana katetera iznosio je 17,842, a incidencija infekcija je bila 3.53 slučajeva na 1,000 kateter dana. Tokom perioda praćenja potvrđene su 63 kateter-povezane infekcije, 54 (85.7%) privremenih i 9 (14.3%) trajnih katetera. Multivarijantnom logistističkom regresionom analizom (granične vrednosti određene receiver operating curve -ROC analizom), kao nezavisni prediktori kateter-povezanih infekcija dobijeni su: vrednost hemoglobina < 95 g/l (p < 0.001) i albumina < VOJNOSANITETSKI PREGLED Vol. 75,No 2 33g/l (p = 0.041), trajanje katetera > 90 dana (p...
We would like to briefly address our recent findings regarding professional satisfaction among anaesthesiologists in Serbia. It is generally wellknown among physicians that the life expectancy of anaesthesiologists is smaller than in other specialties (1). Many resort to the use of cigarettes, drugs, alcohol (2). The number of suicides among anaesthesiologists is significantly larger in comparison with other physicians (3, 4). Needless to say, the level of professional satisfaction is in a direct link with the quality of patient care they are able to provide.To investigate whether there is a lack of satisfaction among anaesthesiologists in our country, we conducted a study aimed at determining if anaesthesiologists in Serbian tertiary hospitals are under chronic stress after 24-hour on-call shifts; if they endure high levels of anxiety; and whether there is a connection between their personality type and alcohol and drug abuse. The study included 60 anaesthesiologists who worked in specialised surgical tertiary health institutions 24 hours on-call. The survey was voluntary and anonymous. All of the physicians involved in the study completed a burnout questionnaire (Oldenburg Burnout Inventory). The mean age of the physicians was 43.1 years (SD=8.1, range 29-63). There was no statistically significant difference in the average age of the physicians in relation to the analysed groups (on call 44.1 years: not on call 42.2 years). Of the physicians on call, 33.3 % were over 40 years of age. Both groups comprised more women than men (on call: 67 % women; not on call: 77 % women) and the distribution by sex was not different in the groups of physicians not on call. As much as 90 % of the anaesthesiologists were on call four or more times per month. They smoked and drank alcohol more than the other doctors in the control group. Altogether 77 % of anaesthesiologists could not rest appropriately after an on-call shift, and if their sleep was interrupted, they needed considerably more time to fall asleep again. Anxiety decreased after taking days off. Stable extraverts had an emotionally stable personality type with the lowest anxiety level. A total of 76.5 % of male and 55.8 % female physicians consumed cigarettes, alcohol, and/or drugs. This difference was not statistically significant. A total of 70.6 % of male and 34.9 % of female anaesthesiologist used cigarettes and/or alcohol. This difference was statistically significant (p=0.027). Several studies have considered the necessary strategies in detecting signs of burnout and concluded that better working conditions reduced stress on the employees; however, the support of colleagues at work and the heads of the hospitals was as equally important as family support systems (5-8).There are stress conditions and burnout amongst Serbian anaesthesiologists. The prevalence of depersonalisation was extremely high in the studied sample. In addition to effects on the health of the anaesthesiologists, burnout and depression may also affect patient care and safety. REFERENCES 1. K...
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