In recent years, in an attempt to substitute the conventional synthetic sound absorption material, natural fibers and their sound absorption properties have been increasingly studied. This is due to the fact that conventional synthetic fiber has potential health risks for human beings and significant environmental impact. In this review, existing and newly emerging natural fiber sound absorbers are summarized and highlighted in three categories: raw material, fiber assembly and composite. The sound absorption mechanism, several widely used prediction models and the popular acoustic characterization methods are presented. The comparison of sound absorption properties between some natural sound absorbers and glass fiber is conducted in two groups, i.e., thin material and thick material. It is found that many natural fibers have comparable sound absorption performance, some of them can be the ideal alternatives to glass fiber, such as kapok fiber, pineapple-leaf fiber and hemp fiber. Last, the conclusion part of this review gives an outlook regarding the promotion of the commercial use of natural fiber by means of theoretical study, efficient and environmentally friendly pretreatment and Life Cycle Assessment.

No abstract

Glioblastoma multiforme (GBM) almost invariably acquires an invasive phenotype, resulting in limited therapeutic options. Protein palmitoylation markedly affects tumorigenesis and malignant progression in GBM. The role of protein palmitoylation in GBM, however, has not been systematically reported. This study aimed to investigate the effect of protein palmitoylation on GBM cell survival and the cell cycle. In this study, most palmitoyltransferases were upregulated in GBM and its cell lines, and protein palmitoylation participated in signaling pathways controlling cell survival and the GBM cell cycle. Inhibition of protein palmitoylation with substrate-analog inhibitors, that is, 2-bromopalmitate, cerulenin, and tunicamycin, induced G 2 cell cycle arrest and cell death in GBM cells through enhanced endoplasmic reticulum (ER) stress. These effects are primarily attributed to the palmitoylation inhibitors activating pro-apoptotic pathways and ER stress signals. Further analysis revealed was the accumulation of SUMOylated XBP1 (X-box binding protein 1) and its transcriptional repression, along with a reduction in XBP1 palmitoylation. Taken together, the present results indicate that protein palmitoylation plays an important role in the survival of GBM cells, further providing a potential therapeutic strategy for GBM.