Heteroatom doping is one of the effective ways to improve the catalytic performances of nanozymes. In the present work, the plasma-assisted controllable doping of nitrogen (N) into MoS 2 nanosheets has been initially proposed, resulting in efficient nanozymes. The so-obtained nanozymes were characterized separately by TEM, XRD, XPS, and FTIR. It was discovered that the resulting N-doped MoS 2 nanosheets could present dramatically enhanced peroxidase-like catalytic activities depending on the plasma treatment time. Particularly, that with the 2-min treatment could display the highest catalytic activity, which is over 3-fold higher than that of pristine MoS 2 , that was also demonstrated by the kinetics studies. Herein, the N 2 plasma treatment could facilitate the N elements to be doped covalently into MoS 2 nanosheets to achieve the increased surface wettability and affinity of nanozymes for the improved access of the electrons and substrates of catalytic reactions. More importantly, the covalent doping of N elements into MoS 2 nanosheets with a lower Fermi level, as evidenced by the DFT analysis, could facilitate the promoted electron transferring, resulting in the enhanced catalysis of N-doped MoS 2 nanozymes, in addition to the high catalytic stability in water. Such a controllable plasma treatment strategy may open a new door toward the large-scale applications for doping heteroatoms into various nanozymes with improved catalysis performances.

NLR and PLR levels may be valuable indexes for lymph node metastasis. Although both the PLR and NLR may have prognostic value of gastric cancer patients, NLR is better to predict overall survival than PLR.

Background Blood counting and the liver function tests, as the routine examinations, can reflect the immune and nutritional status of the body, our aim is to assess the prognostic significance of serum gamma-glutamyltransferase (GGT) levels and AST/ALT in primary hepatic carcinoma. Methods Clinico-pathological data of 414 patients with primary hepatic carcinoma in the 1st Affiliated Hospital of Anhui Medical College between January 2007 to January 2014 was analyzed retrospectively in this study. Survival curves were described by Kaplan-Meier method and compared by Log-rank test, univariate and multivariate analysis were used to identify the prognostic factors. Results GGT was positively correlated with the tumor size( P = 0.000), tumor volume ( P = 0.000), tumor volume percent ( P = 0.004), TNM stage( P = 0.009), 1-year survival rate ( P = 0.000), 3- years survival rate ( P = 0.000) and 5-years survival rate( P = 0.000). The serum ALT/AST was significantly correlated with age ( P = 0.047), tumor size( P = 0.002), tumor volume ( P = 0.010), tumor volume percent ( P = 0.005), TNM stage( P = 0.006), liver cirrhosis( P = 0.003), 3- years survival rate ( P = 0.032) and 5-years survival rate( P = 0.000). The Kaplan-Meier curves showed that the patients with primary hepatic carcinoma had a longer time in the low GGT group and low AST/ALT group, showing a significant difference ( P < 0.05). The univariate and multivariate analyses showed that TNM stage, differentiation grade, tumor volume, GGT and AST/ALT were independent factors for predicting overall survival rate of primary hepatic carcinoma patients. Conclusions GGT and AST/ALT were independent factors for predicting overall survival rate of primary hepatic carcinoma patients.

No abstract

However, for systems such as hydro turbine generating sets (HTGS) where the control and regulation is frequently applied, the shafting safety and stabilization in transient state is then a key factor. The shafting transient state inevitably involves multi-parameter domain, multi-field coupling and coupling dynamics. In this paper, the relative value form of the Lagrange function and its equations have been established by defining the base value system of the shafting. Taking the rotation angle and the angular speed of the shafting as a link, the shafting lateral vibration and generator equations are integrated into the framework of the generalized Hamiltonian system. The generalized Hamiltonian control model is thus established. To make the model be more general, additional forces of the shafting are taken as the input excitation in proposed model. The control system of the HTGS can be easily connected with the shafting model to form the whole simulation system of the HTGS. It is expected that this study will build a foundation for the coupling dynamics theory using the generalized Hamiltonian theory to investigate coupling dynamic mechanism between the shafting vibration, transient of hydro turbine generating sets and additional forces of the shafting.