Review question / Objective: This systematic review aims to evaluate the efficacy of progestin-primed ovarian stimulation (PPOS) on reproductive outcomes in patients with polycystic ovary syndrome (PCOS) undergoing assisted reproductive techniques. Condition being studied: PCOS is a common endocrine disorder that can cause infertility in women of childbearing age. The PPOS protocol, which involves oral progestins with gonadotropin (Gn), has been shown to be effective and safe in treating patients with PCOS. However, the question of whether PPOS provides a significant benefit over conventional GnRH analogue protocols in PCOS patients is still controversial.
Review question / Objective: This meta-analysis aims to evaluate whether intracytoplasmic sperm injection (ICSI) improved reproductive outcomes for non-male factor infertility versus in vitro fertilization (IVF). Condition being studied: The use of ICSI has increased dramatically in recent years and is being applied for indications other than male factor infertility. However, despite its increased use, there is no clear evidence of the benefit of using ICSI over conventional IVF for non-male factor infertility. Eligibility criteria: Studies will be excluded if one of the following conditions is met: (1) unqualified male perm count and motility; (2) rescued ICSI; (3) non-RCTs of study design; (4) a significant amount of research data is missing or not available.
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