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Strategy studies have been a well-established field in second language writing research and this article investigates English as a foreign language (EFL) learners' writing strategy use from a sociocultural perspective. Unlike the traditional focus on internal cognitive mechanisms in writing strategy studies, this sociocultural approach highlights the dialectic relationship between cognition and the sociocultural context and the importance of mediating resources in strategy use. Six proficient English majors from a Chinese university participated in the study, and data about their writing experience were collected through interviews. The findings showed that the participants used four types of writing strategies: artifact-mediated, rule-mediated, community-mediated, and role-mediated strategies. Other features of their strategy use include the diversity of mediating resources, idiosyncratic use of these resources, and the common goal to enhance their language knowledge and writing ability. Drawing on these findings, it is suggested that teachers can reconfigure the sociocultural context of writing activities to help students enhance their strategy use and possible ways include artifact manipulation and community construction.

Complement receptor of immunoglobulin superfamily (CRIg) is expressed on liver macrophages and directly binds complement component C3b or Gram-positive bacteria to mediate phagocytosis. CRIg plays important roles in several immune-mediated diseases, but it is not clear how its pathogen recognition and phagocytic functions maintain homeostasis and prevent disease. We previously associated cytolysin-positive Enterococcus faecalis with severity of alcohol-related liver disease. Here, we demonstrate that CRIg is reduced in liver tissues from patients with alcohol-related liver disease. CRIg-deficient mice developed more severe ethanol-induced liver disease than wild-type mice; disease severity was reduced with loss of toll-like receptor 2. CRIg-deficient mice were less efficient than wild-type mice at clearing Gram-positive bacteria such as Enterococcus faecalis that had translocated from gut to liver. Administration of the soluble extracellular domain CRIg–Ig protein protected mice from ethanol-induced steatohepatitis. Our findings indicate that ethanol impairs hepatic clearance of translocated pathobionts, via decreased hepatic CRIg, which facilitates progression of liver disease.

The concentrations and formation pathways of mono-to octa-chlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) were investigated in main organochemical industries. High levels of PCDDs and PCDFs were detected. The total concentrations of 27 PCDD/F congeners in chloranil, 2,4-D, and 1,4-dichlorobenzene were 5302397 ± 8944449, 20963 ± 15908, and 242 ± 67 pg g −1 , respectively, and the less-chlorinated PCDD/F levels were 12006 ± 20155, 9536 ± 5594, and 195 ± 94 pg g −1 , respectively. The distribution trends of less and more chlorinated PCDD/Fs were similar in different chemical plants because of their similar formation pathways, which may also be related to the degree of chlorination of chemical products and purification processes.