Hydrogen peroxide (H2O2) has exhibited huge application value in many fields including chemical synthesis, medicine, environmental remediation, and fuel cells. Traditional anthraquinone method for H2O2 commercial production has emerged the drawbacks of toxicity, H2 consumption and high energy input. Photocatalytic production of H2O2, which only requires water, oxygen, solar light and catalyst, is a novel and green technique, and potentially becomes one of the substitutes for anthraquinone method. Herein, we comprehensively review the research progress in the reported semiconductor catalysts, their modification strategies, as well as the related photocatalysis systems and mechanisms for the light driven H2O2 production. In detail, the photocatalysts are introduced from different families including ZnO, g-C3N4, TiO2, metal complexes, metal sulfides, Bi containing semiconductors, and carbon materials. In the meantime, their modification strategies are systematically evaluated aiming at the improvement in the structures and the photoelectrical properties of semiconductors, as well as their effective activation of molecular O2, and inhibition of H2O2 decomposition. Finally, this review is concluded with a brief summary and outlook, and the major challenges for the development of photocatalytic H2O2 production over the emerging semiconductor photocatalysts. This review is expected to provide a theoretical and understanding foundation for the development of photocatalytic H2O2 production.
Aims:Our team tested spinal cord fusion (SCF) using the neuroprotective agent polyethylene glycol (PEG) in different animal (mice, rats, and beagles) models with complete spinal cord transection. To further explore the application of SCF for the treatment of paraplegic patients, we developed a new clinical procedure for SCF called vascular pedicle hemisected spinal cord transplantation (vSCT) and tested this procedure in eight paraplegic participants.Methods: Eight paraplegic participants (American Spinal Injury Association, ASIA: A) were enrolled and treated with vSCT (PEG was applied to the sites of spinal cord transplantation). Pre-and postoperative pain intensities, neurologic assessments, electrophysiologic monitoring, and neuroimaging examinations were recorded.Results: Of the eight paraplegic participants who completed vSCT, objective improvements occurred in motor function for one participant, in electrophysiologic motor-evoked potentials for another participant, in re-establishment of white matter continuity in three participants, in autonomic nerve function in seven participants, and in symptoms of cord central pain for seven participants.
Conclusions:The postoperative recovery of paraplegic participants demonstrated the clinical feasibility and efficacy of vSCT in re-establishing the continuity of spinal nerve
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