The Image Biomarker Standardization Initiative validated consensus-based reference values for 169 radiomics features, thus enabling calibration and verification of radiomics software. Key results: • research teams found agreement for calculation of 169 radiomics features derived from a digital phantom and a human lung cancer on CT scan. • Of these 169 candidate radiomics features, good to excellent reproducibility was achieved for 167 radiomics features using MRI, 18F-FDG PET and CT images obtained in 51 patients with soft-tissue sarcoma.

Purpose: Osteoradionecrosis (ORN) of the mandible represents a severe, debilitating complication of radiation therapy (RT) for head and neck cancer (HNC). At present, no normal tissue complication probability (NTCP) models for risk of ORN exist. The aim of this study was to develop a multivariable clinical/dose-based NTCP model for the prediction of ORN any grade (ORN I-IV ) and grade IV (ORN IV ) after RT ( §chemotherapy) in patients with HNC.

No abstract