A survey was conducted to obtain a greater understanding of the costs involved in operating a biobank. The anonymized survey data was then used to develop the BEMT, a cost modeling tool for biobanks. Users of the tool will be able to create a cost profile for their biobanks' specimens, products and services, establish pricing, and allocate costs for biospecimens based on percent cost recovered, and perform project-specific cost analyses and financial forecasting.
Open access to well-annotated samples and the challenges that poses to sustainability Open access to well-annotated samples and the privacy challenges Challenges are magnified due to increasing amounts of data of unknown quality
Chapter 3 highlights the value of biobank collections for biomarker development and validation, specifically providing an overview of critical issues in the biobanking pathway that impact biomarker research results. The chapter commences with an overview of the biobank-biomarker collaborative landscape in an effort to elucidate, key planning considerations for enhancing biomarker validation and research. Universal challenges in biospecimen collection and utilization are discussed. Four key areas of dysfunction are outlined: unsustainable biobanking operational models, difficulties in locating and accessing quality biospecimens with appropriate associated data, inefficient research business practices (resulting in inability to engage in timely collaborations) and limited prevalence of suitable biospecimen collections. Recommendations are presented as to how these critical challenges may be ameliorated. Thoughts are then offered as to how biospecimen and biomedical research practices may be improved to optimize and accelerate incidence of relevant biomarker research outcomes.
Temperature data collected heightened observations of sample temperature variability. Prevalence of bar-code label read failure and issues affecting reliability of barcode performance may be under-reported and unrecognized in sample management practice, particularly when the temperatures are lower than -60°C. It appears the bluechiip(®) tracking technology may offer increased reliability over one-dimensional (1D) bar-coding technology; however while promising these findings require validation in future trials, including two-dimensional (2D) bar-coding technologies.
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