Objective-The purpose of this study was to determine whether the degree of anterior compartment (bladder) and apical compartment (cervix) prolapse are correlated, and whether 2 anterior compartment elements (urethra and bladder) are related at maximal Valsalva.Study design-Women with a complete spectrum of pelvic support were recruited for a pelvic support study. Dynamic magnetic resonance scans were taken during Valsalva. A convenience sample of 153 women with a mean age of 53.3 ± 12.5 (SD) years with a uterus in situ was studied. Anterior compartment status was assessed by the most caudal bladder point and the internal urinary meatus. The external cervical os was used to assess the apical compartment. The position of the bladder, urethra, and uterus were determined in 20 nulliparous women to determine their reference locations. The distances of each structure below the reference positions were calculated at maximum Valsalva.Results-Average distances of the bladder base, urethra, and uterus from the reference positions at maximal Valsalva were 4.1 ± 2.4 cm, 3.1 ± 1.3 cm, and 4.3 ± 2.4 cm, respectively. The Pearson correlation coefficient of the relationship between the bladder base and uterine distances was r = 0.73 (r 2 = 0.53). The Pearson correlation coefficient of the bladder distance and urethral distance was r = 0.82 (r 2 = 0.67).Conclusion-Half of the observed variation in anterior compartment support may be explained by apical support. KeywordsPelvic organ prolapse; MRI; Cystocele; Uterine prolapse; Biomechanics Pelvic organ prolapse is a distressing and debilitating condition for women. It requires surgery in approximately 200,000 American women each year, 1 making it the pelvic floor disorder most often requiring surgical repair.There are many different combinations of support defects in women who have pelvic organ prolapse. They can involve the anterior compartment, the posterior compartment, or the apical segment. The nature of these problems relates to the structural supports of the vagina and uterus
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