Ovarian cystadenofibroma are rare slow growing benign epithelial ovarian neoplasms. It usually occurs as solid and cystic component. Most of the tumours are asymptomatic and detected incidentally during abdominal ultrasound for some other purpose. They may mimick malignant neoplasm with their gross appearance and imaging modalities. So a diagnosis of serous papillary cystadenofibroma of ovary on frozen section can save the patient from unwanted extensive surgery. We here in discuss a case of serous papillary cystadenofibroma of ovary in a 45 year old multipara that was diagnosed initially on frozen section and later confirmed on histopathology, thus highlighting the role of frozen section in diagnosis of intraoperative ovarian neoplasms.
Polycystic kidney disease is a rare developmental anomaly inherited as Autosomal dominant or recessive. Autosomal recessive polycystic kidney disease (ARPKD) is an intractable cystic renal disease that results in chronic renal failure. It has a profound effect on growing fetus and result in serious implications if pregnancy is continued in the long run after being detected on sonography. Although prenatal imaging studies and clinical findings are suggestive of ARPKD it can be accurately diagnosed by histopathology if an autopsy is performed in cases of infant death. In this article we here in present the features of ARPKD diagnosed antenatally by USG in a 22 yr female, and was confirmed further by fetal autopsy.
Introduction: Obesity, emerging as a worldwide health burden having potential risk for development of atherosclerosis, diabetes, coagulopathy, arthritis and metabolic syndrome. Obesity is classified in terms of various anthropometric modalities like Body Mass Index (BMI), Waist Circumference (WC) and Waist Hip Ratio (WHR) etc. Adipocyte secretes adiponectin that has an important role in energy homeostasis and lipid metabolism. Adiponectin level reduces in obesity and its deficiency results in higher incidence of insulin resistance. Adiponectin has insulin sensitising, antiatherogenic and anti inflammatory properties. Aim: To compare the level of serum adiponectin, fasting plasma insulin and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) in healthy obese individuals with healthy non obese controls and also to find out the correlation of serum adiponectin with fasting plasma insulin level and HOMA-IR in healthy obese cases. Materials and Methods: This case-control study was conducted in Department of Biochemistry, MKCG MCH, Berhampur, Odisha, India, during the period of October 2019 to October 2020 which included 86 subjects. Of which 43 were healthy obese individuals and 43 were age and sex matched healthy non obese volunteers, in the age group of 20-45 years were taken as controls. About 4 mL of whole blood was collected to measure fasting plasma glucose, fasting plasma insulin and serum adiponectin. Statistical Package for the Social Sciences (SPSS) version 16.0 was used to do the statistical analysis and for correlation Pearson correlation test was done. Results: In present study, maximum cases and controls were within the range of 20-35 years. Out of 43 cases, 25 were males and 18 were females and out of 43 controls, 27 were males and 16 were females. Insulin resistance and Fasting Plasma Glucose were significantly higher in healthy obese cases as compared to controls. Serum adiponectin in cases (2.35±0.77) was found to be significantly lower than controls (8.10±2.98). Present study found statistically significant negative correlation of serum adiponectin with fasting plasma insulin (r=-0.918, p<0.001) and HOMA-IR (r=-0.934, p<0.001). Conclusion: Negative correlation of adiponectin and positive correlation of insulin resistance in obesity suggest inflammation which may lead to development of metabolic syndrome. So adiponectin is a target for future research to reduce morbidity and mortality in relation to obesity.
Congenital birth defects are major cause of poor health among infants affecting their survivability. Although such anomalies of the eyes are uncommon, the impact they have on the quality of life are more than significant. This study aimed to describe the clinical profile of congenital ocular anomalies with various epidemiological parameters in a tertiary health care center in western Orissa. The study screened 3674 patients, in the age group of 0 -14 years, who were delivered or attended the out-patient Department V.S.S. Medical College, Burla, Odisha and included 151 eyes of 99 cases of various types of congenital anomalies. Detailed history and other necessary data were collected by trained ophthalmologists and descriptive analyses performed. The incidence of congenital ocular anomalies was found to be 2.69%. Nasolacrimal duct anomalies (47 eyes) were the most frequently occurring congenital ocular anomaly (31.1%); followed by congenital cataract (41 cases; 27.3%) and coloboma eye (18 cases; 11.9%).There was a slight male preponderance, constituting 56.57% of the total cases. Majority of the patients were less than 5 years old (68 %) and the incidence of congenital ocular anomalies to be highest 11481 (68.69%) in the age group of 0 -5 years. Single eye involvement was seen in 47 cases (47.47%), whereas bilateral involvement was seen in 52 (52.53%) cases. History of consanguinity was found to be present in 13.13% of cases, with increased risk of bilateral involvement (84.6% cases). The most common presenting symptom was defective vision (38.4%), followed by watering from eyes (32.3%) and white pupillary reflex (14.1%). A total of 60 eyes (39.7%) required surgery. Congenital ocular anomalies are a common cause of ocular morbidity, comprising 2.7% of total cases in the paediatric age group. Early diagnosis, referral and appropriate intervention would help prevent majority of permanent sequelae in congenital ocular anomalies.
This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.