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The incidence and quantities of dimethyltryptamine and O-methylbufotenine were studied in the cerebrospinal fluid of patients suffering acute schizophrenic illnesses and in surgical and neurological control groups. Some schizophrenic patients have higher levels of both amines than do controls, though the differences in distribution did not reach statistical significance in the sample studied. The gas-chromatographic technique used is sensitive at the low picogram level.

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In antiquity, these powers and principles of the transpersonal levels of the psyche were personified and given the names of gods and goddesses. Today they are thought of as a priori fields or patterns of information that are not dependent on any learned or environmental factors. These organizing principles correspond to the traditional notion of spirit, an unseen world that radically affects human life. To the extent that we take into account the psyche's spiritual potentials, depth psychology and spirituality are two approaches to the same phenomena.