Bowel preparation is the basis of colonoscopy, and adequate bowel preparation is essential to the success of colonoscopy. Studies have been reported that telephone intervention can improve the quality of bowel preparation, while it remains unclear regarding effectiveness with the elderly. The purpose of this study was to evaluate the effect of telephone intervention on the quality of bowel preparation for colonoscopy in elderly outpatients. In total, 162 outpatients older than 65 years were enrolled and randomly divided into a control group and a study group. Patients in the study group were re-educated through telephone by a specific nurse 2 days before colonoscopy, whereas participants in the control group received education only on the day of appointment. The Ottawa score was used to evaluate the quality of bowel preparation between the two groups. In this study, no significant differences were observed in age, gender, body mass index, educational level, smoking and/or alcohol drinking, waiting time to colonoscopy, reasons for colonoscopy, and colonoscopic findings between the control group and the study group. Participants in the study group had higher adequate bowel preparation and compliance than the control group (83.1% vs. 59.5%, p = .03; 96.4% vs. 74.7%, p < .001). Univariate analysis showed that only noncompliance with start time was significantly associated with satisfactory bowel preparation in elderly patients. In conclusion, telephone intervention 2 days before colonoscopy can improve the quality of bowel preparation in the elderly.
evaluated. Furthermore, pre-treatment structures in the microbiome were compared with structures 1 week and 2 months after treatment. Results Alpha diversity analysis showed that both richness and evenness were recovered to pre-treatment levels at 2 months after eradication therapy. There were almost no differences in bacterial species abundance between pre-and post-treatment samples in beta diversity analysis. Although the relative abundance of Bacteroidetes tended to increase and Actinobacteria significantly decreased immediately after eradication, the taxonomic composition was similar to that pre-eradication at 2 months post-eradication. However, 2 students showed significant structural changes in their relative abundances at the phylum level. Conclusions This study suggests a limited impact of H. pylori eradication therapy on the gut microbiome in healthy midteenagers. However, we should continuously monitor the effects of changes to the gut microbiome caused by antibiotic use.
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