Landfills are mostly used to manage solid waste in Ho Chi Minh City, Vietnam. Due to inappropriate administration, there have been numerous issues over the years relating to odor and leachate. The purpose of this study is to explore the impact of odor stemming from Da Phuoc landfill site on surrounding areas. A questionnaire survey was administered through face-to-face interviews with 409 residents living in the affected areas. The findings of this study indicate that the odor perception of residents significantly influences their attitudes towards waste disposal sites. The results show that odor affects not only the region around municipal solid waste (MSW) treatment facilities but regions more than 7 km away as well. The data indicates that the odor emanating from the MSW disposal site negatively affects the daily life of many residents. This study is an effort to finding a solution to reduce the impact of odor generated from the landfill site on nearby residential areas.
Appearance for the first time from Wuhan, China, the SARS-CoV-2
rapidly outbreaks worldwide and causes a serious global health issue. The
effective treatment for SARS-CoV-2 is still unavailable. Therefore, in this
work, we have tried to rapidly predict a list of potential inhibitors for
SARS-CoV-2 main protease (Mpro) using a combination of molecular docking and
fast pulling of ligand (FPL) simulations. The approaches were initially
validated over a set of eleven available inhibitors. Both Autodock Vina and FPL
calculations adopted good consistent results with the respective experiment
with correlation coefficients of R_Dock=0.72 ± 0.14 and R_W = -0.76 ± 0.10, respectively. The combined approaches were
then utilized to predict possible inhibitors, which were selected from a ZINC15
sub-database, for SARS-CoV-2 Mpro. Twenty compounds were suggested to be able
to bind well to SARS-CoV-2 Mpro. The obtained results probably lead to enhance
COVID-19 therapy.
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