Objective. The objective is to compare parameters related to lens position measured using anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in patients with senile cataract and perform a consistency analysis. Methods. This prospective study included 102 patients (102 eyes) scheduled for simple cataract surgery. Among the total patients, 44 were men, and 58 were women. AS-OCT (sitting) and UBM (lying) were used to measure the anterior chamber depth (ACD) in horizontal and vertical orientations and the iris-lens contact distance (ILCD) and iris-lens angle (ILA) in inferior, superior, nasal, and temporal quadrants. Paired-sample t-test was used to compare ACD, ILCD, and ILA measurements of the two methods, while Pearson’s linear correlation and Bland-Altman analyses were used to analyze the correlation and consistency of the two results. Results. The horizontal (2.499 ± 0.464 mm) and vertical (2.531 ± 0.463 mm) ACD measured using AS-OCT and the horizontal (2.556 ± 0.467 mm) and vertical (2.563 ± 0.479 mm) ACD measured using UBM were significantly different ( P < 0.001 ); moreover, the results showed good correlation and agreement. A significant difference was observed between the two methods in terms of ILCD measured in inferior, superior, nasal, and temporal quadrants ( P < 0.001 ), and a significant correlation was found between measurements of both methods ( P < 0.001 ). Approximately 3.92% (4/102), 0.98% (1/102), 3.92% (4/102), and 2.94% (3/102) of points were outside the 95% limits of agreement in the four quadrants, respectively, and the agreement of the results was good. ILA measured using both methods differed in inferior, superior, nasal, and temporal quadrants ( P = 0.003 , 0.011, 0.001, 0.001, respectively), and the correlation was good ( P < 0.001 ). The percentage of points outside the 95% limit was higher in inferior, superior, nasal, and temporal quadrants (4.90% (5/102), 5.88% (6/102), 5.88% (6/102), and 6.86% (7/102)) with poor agreement of the results. Conclusions. The correlation between AS-OCT and UBM in terms of measuring lens position-related parameters was good, but the agreement was unstable. The differences in measurement position (sitting and supine) and/or measurement methods (optics and ultrasound) may lead to variability in results.

Purpose. This study is aimed at evaluating the effects of hemodialysis on intraocular pressure (IOP) and exploring the possible factors affecting IOP. Methods. Fifty-two patients with hemodialysis (HD) that were diagnosed with chronic renal failure by nephrology were divided into four groups: wide angle, narrow angle, extremely narrow angle, and closed angle. IOP, central anterior chamber depth (ACD), lens thickness (LT), angle opening distance (AOD), trabecular-iris angle (TIA), iris thickness (IT), and ciliary body thickness (CBT) were recorded before and after HD. The Pearson coefficient test was used to determine correlations among changes in IOP and AOD, ACD, TIA, IT, CBT, and LT. Results. The IOP in the extremely narrow angle group had significant difference compared with that in the wide angle group and narrow angle group ( P < 0.05 , P < 0.01 ). In the narrow angle group, change in LT was positively correlated with change in IOP ( P < 0.05 ). In the extremely narrow angle group, change in LT was positively correlated with change in IOP (P<0.01), whereas changes in AOD and TIA were negatively correlated with change in IOP ( P < 0.01 ; P < 0.05 ). Conclusion. The effect of HD on IOP varies with the structure of the anterior chamber. The increasing of IOP in the extremely narrow-angle group is related with the changes of structure of anterior chamber.

Purpose To study the classifications of qualitative characteristics on the angle configurations in the acute primary angle closure (APAC) and fellow eyes by ultrasound biomicroscopy (UBM). Methods A total of 131 patients (262 eyes) were researched retrospectively. The qualitative parameters from UBM images were classified into iris form (IF), ciliary body configuration (CBC), basal iris thickness (BIT), iris convexity (IC), iris insert (II), iris angulation (IA), ciliary body size (CBS) and ciliary body position (CBP). Comparative analyses between the APAC (case group) and fellow (control group) eyes were performed. Results There were significant differences in IF, CBC, IC, II, CBS, CBP between the case group and control group in all quadrants ( P <0.001). The IA of the case group and control group presented significant difference in all quadrants ( P =0.001). However, there was not a significant difference in BIT between the case group and control group in all quadrants ( P =0.495). The case group had fewer parallelogram-like and mushroom-like and more cone-like and hook-like CBCs than the control group ( P <0.001). Conclusion Multiple ciliary body configurations can influence the stability of the lens and the anatomic configuration of the anterior chamber angle indirectly. New qualitative classification system of UBM may be more intuitionistic and refined to reflect the angle configurations to help clinical practice.

Background The spatial position of the lens in patients with cortical age-related cataract (CARC) is unclear. We investigated a basis for the assessment of visual quality after cataract surgery by analysing the ultrasound biomicroscopic characteristics of the biological parameters of the lens in patients with (CARC) Methods In this retrospective study, 119 patients (50 males and 69 females, totalling 238 eyes) with CARC who underwent simple cataract surgery were selected. The lens thickness (LT), axial length (AL), anterior chamber depth (ACD), lens vault (LV), trabecular-iris angle (TIA), iris-lens angle (ILA), iris-lens contact distance (ILCD) were measured by A-scan ultrasound and ultrasound biomicroscopy. The corresponding lens position (LP) and relative lens position (RLP) were calculated. Results LP was greater in men than in women (P < 0.05), LV was smaller in men than in women (P = 0.002), ILA and ILCD were not statistically significant (P = 0.072 and P = 0.854, respectively). There were significant differences in TIA, ILA, and ILCD in the four quadrants (all P < 0.05), with a trend in the distribution of TIA: superior < inferior < nasal < temporal, ILA: nasal < inferior < temporal < superior, and ILCD: superior < temporal < inferior < nasal. Conclusions The lens protrudes more obviously in females than in males and the lens tilts to a certain extent with the increase of age and tends to be more upward and temporal in the supine position. Therefore, trends in lens-related parameters in patients with CARC should be taken seriously.

Purpose To investigate the differences in parameters related to angle configuration and lens position in patients with cortical age-related cataract by ultrasound biomicroscopy (UBM) in different body positions. Methods Prospective study with 55 patients with cortical age-related cataract proposed for phacoemulsification, examined using a Compact Touch STS UBM (Quantel Medical, France). UBM bag/balloon technology was applied to measure the central anterior chamber depth (ACD) and lens vault (LV) in horizontal and vertical orientation in sitting and supine positions, angle opening distance (AOD500), trabecular iris angle (TIA) and iris lens angle (ILA) in four quadrants: superior, inferior, nasal, and temporal. Results We found no significant difference in ACD between sitting and supine positions ( p = 0.053); LV was significantly greater in the supine position ( p < 0.001); AOD500 in superior and inferior quadrants were significantly longer in the sitting position ( p = 0.001; p < 0.001); TIA in superior and inferior quadrants was significantly greater in the sitting position ( p < 0.001; p < 0.001), and TIA max-min was significantly smaller in the sitting position ( p = 0.001); ILA in temporal quadrant was significantly larger in the sitting position ( p = 0.015) and ILA max-min was significantly smaller in the sitting position ( p < 0.001). Conclusion The anterior chamber angle was narrower and the lens was positioned more anteriorly in the supine than in the sitting position in cortical age-related cataract. Different positions may affect the angle configuration and the relative space of lens through different directions of mechanics and modes of action.