Magnetic resonance imaging is a key diagnostic tool in modern healthcare, yet it can be cost-prohibitive given the high installation, maintenance and operation costs of the machinery. There are approximately seven scanners per million inhabitants and over 90% are concentrated in high-income countries. We describe an ultra-low-field brain MRI scanner that operates using a standard AC power outlet and is low cost to build. Using a permanent 0.055 Tesla Samarium-cobalt magnet and deep learning for cancellation of electromagnetic interference, it requires neither magnetic nor radiofrequency shielding cages. The scanner is compact, mobile, and acoustically quiet during scanning. We implement four standard clinical neuroimaging protocols (T1- and T2-weighted, fluid-attenuated inversion recovery like, and diffusion-weighted imaging) on this system, and demonstrate preliminary feasibility in diagnosing brain tumor and stroke. Such technology has the potential to meet clinical needs at point of care or in low and middle income countries.

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At present, MRI scans are typically performed inside fully enclosed radiofrequency (RF) shielding rooms, posing stringent installation requirements and causing patient discomfort. We aim to eliminate electromagnetic interference (EMI) for MRI with no or incomplete RF shielding. In this study, a method of active sensing and deep learning EMI prediction is presented to model, predict, and remove EMI signal components from acquired MRI signals. Specifically, during each MRI scan, separate EMI‐sensing coils placed in various locations are utilized to simultaneously sample external and internal EMI signals within two windows (for both conventional MRI signal acquisition and EMI characterization acquisition). A convolution neural network model is trained using the EMI characterization data to relate EMI signals detected by EMI‐sensing coils to EMI signals in the MRI receive coil. This model is then used to retrospectively predict and remove EMI signal components detected by the MRI receive coil during the MRI signal acquisition window. This strategy was implemented on a low‐cost ultralow‐field 0.055 T permanent magnet MRI scanner without RF shielding. It produced final image signal‐to‐noise ratios that were comparable with those obtained using a fully enclosed RF shielding cage, and outperformed existing analytical EMI elimination methods (i.e., spectral domain transfer function and external dynamic interference estimation and removal [EDITER] methods). A preliminary experiment also demonstrated its applicability on a 1.5 T superconducting magnet MRI scanner with incomplete RF shielding. Altogether, the results demonstrated that the proposed method was highly effective in predicting and removing various EMI signals from both external environments and internal scanner electronics at both 0.055 T (2.3 MHz) and 1.5 T (63.9 MHz). The proposed strategy enables shielding‐free MRI. The concept is relatively simple and is potentially applicable to other RF signal detection scenarios in the presence of external and/or internal EMI.