Percutaneous coronary intervention for acute coronary syndrome or non–ST-elevation myocardial infarction requires the use of potent oral and intravenous anti-platelet and antithrombin medications. Although these potent antithrombotic agents and regimens may increase the effectiveness of percutaneous coronary intervention, they are also generally associated with an increased risk of vascular access complications such as hematoma, retroperitoneal hematoma, pseudoaneurysm, arterial occlusion, and arteriovenous fistula, which in turn are associated with increased morbidity, mortality, and costs. Risk factors predisposing patients to these complications are both modifiable (procedure technique, medications, hemostasis method) and nonmodifiable (sex, age, body mass index, blood pressure, renal function). Patients’ risks can be reduced by nurses who are knowledgeable about these risk factors and identify complications before they become problematic.

Of the 413 patients, 68 (16.5%) had a complication. Sixty-four (15.5%) developed hematomas ranging in size from 1 to 5 cm (n = 35, 8.5%) to greater than 5 cm (n = 29, 7.0%), 6 experienced bleeding (1.5%), 4 (1%) had arteriovenous fistulas, and 3 (0.7%) developed pseudoaneurysms. There were no significant differences for complications using manual, C-clamp, or arterial vascular closure device. Patients with a higher systolic blood pressure (135 vs 129; df = 410, P = .025) and of older age (66 vs 63; df = 411, P = .016) were significantly more likely to have complications. Clinically significant major vascular complications were low. Arterial closure devices, mechanical C-clamp, and manual compression all provide low and comparable complication risks following sheath removal in the era of antiplatelet and antithrombotic therapies. Patients who are older and those with elevated blood pressure should have their femoral access site closely monitored and be observed for vascular complications.

HEALTH CARE WORKERS (HCWs) are at risk for acquiring infections such as human immunodeficiency virus, hepatitis B virus, hepatitis C, and tuberculosis from blood and body fluids. The Centers for Disease Control established guidelines known as universal precautions (UPs) to prevent transmission of blood-borne pathogens in hospital settings, but UPs are not universally followed. CNSs are in a unique position to enhance the practice of UPs and decrease the HCW's risk-taking behavior. CNSs need to identify risk-taking behaviors and help HCWs make the right decision in risky situations. Reasons cited for noncompliance with UPs were habit, forgetfulness, influence of the nurse manager, and perceptions that barrier precautions hinder the ability to perform procedures successfully. Suggestions for improving compliance with UPs were better enforcement of guidelines, a policy mandating compliance, easy and available access to supplies, replacement of hazardous devices with safer ones, and discussion with HCWs on decision making in risky situations. CNSs possess the credibility in the clinical arena to effect change through clinical expertise, role modeling, and collaboration with HCWs.

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