2-Chloro-2-methyl-l-phenyl-l-propanone. Reaction of isobutyrophenone with lithium hexamethyldisilazane in THF (53%)-hexane (34%)-HMPA (13%) with Me2C(N02)Cl for 1 h at 25 °C gave 78% of the chloro ketone analyzed by the NMR singlet at 1.90 and identified by comparison of the NMR spectra and gas chromatography retention time with those of an authentic sample.Reaction of PhC(OLi)==CHCH3 with Me2C(N02)2 and Me2C(N02)S02PhMe-p. In addition to lc and 3c significant amounts of 5c (X = NCy and 5d (X = p-MePhSO^w ere formed. These products were identified by GC/MS and analyzed by NMR. For PhCOCH(Me)N02 analysis was based on the signal at 6.33 (q, J = 7 Hz, 1 H) in CDC13, while for PhCOCH(Me)-S02PhMe-p analysis was based on signals at 1.54 (d, J = 7 Hz, 3 H), 2.34 (s, 3 H), 5.27 (q, J = 7 Hz, 1 H) in CDC13 and the GC/mass spectrum, m/e 288 (M+), 155 (p-MePhS02), 139 (C6-H4S02), 133 (PhCOCHMe).
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