Toward a Novel Approach to Bis-β-Lactam Synthesis Using Vilsmeier Reagent as an Efficient Entity via Staudinger Cycloaddition Reaction. -Vilsmeier reagent is shown to act as acid activator reagent for the direct [2 + 2] ketene-imine cycloaddition of acetic acid (II) and bisimines (I). In all cases, the process affords cis,cis-bis-β-lactams (III) (8 examples). -(MESHRAM*, J.; ALI, P.; TIWARI, V.; J. Heterocycl.
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