At present, health-care systems in the United States face enormous challenges in providing quality care, characterized by safe, effective, efficient, patientcentered, timely, and equitable care while containing health-care costs [1,2]. To understand and address patients' increasingly complicated health-care needs, we need safe access to quality information that is characterized by integrity, reliability, and accuracy [3], and establish mutually beneficial relationships among a multidisciplinary team of professionals [4].Traditional paper-based clinical workflow produces many issues such as illegible handwriting, inconvenient access, the possibility of computational prescribing errors, inadequate patient hand-offs, and drug administration errors. These problems can lead to medical errors, omissions, and duplications and, ultimately, poor patient outcomes and compromised quality of care [2].Electronic health records (EHR) is a major achievement in the health information technology [5]. It is deemed a promising solution to improve the interoperability of patients' information across health-care settings and achieve a more cost-effective, safer, and higher quality of care [3,6]. Electronic medical records
BackgroundPeripheral neuropathy (PN), including numbness, loss of sensation, paresthesia, a burning sensation, and stabbing pain in extremities, is a common complication in people with human immunodeficiency virus (PHIV). Medications commonly used to treat HIV-related PN are not effective and lead to many side effects. HIV-related PN symptoms may be alleviated or treated with a series of therapeutic Chinese foot massages (TCFM), which are non-invasive and relatively safe. However, relevant studies are lacking.Study designThis proposed trial is a prospective, two-arm, parallel, double-blinded, randomized controlled trial.AimThis proposed trial aims to assess the effectiveness of TCFM on HIV-related PN in people with HIV (PHIV).OutcomesThe primary outcomes, measured at baseline, end of TCFM/placebo, and twelve weeks after, include (1), lower extremity pain, (2) lower extremity functioning, and (3) health-related quality of life. The secondary outcomes, measured throughout the trial process, include (1) recruitment and completion rate (No. of referred, No. of eligible, No. of enrolled, No. of withdrawals, trial recruitment rate, and trial completion rate), (2) participants' safety (No. and severity of adverse events), (3) treatment adherence (average time of each message session, No. of completed sessions, and No. of missed sessions), and (4) compliance (No. of participants completing the trial following the initial group assignment).Sample sizeAn estimated 142 participants in total, or 71 participants in each arm, will be needed for this trial.Trial statusThis trial was registered at ClinicalTrials.gov of the National Institute of Health on Oct 26, 2022 (ClinicalTrials.gov Identifier: NCT05596123). The researchers expect to recruit participants starting in Feb. 2023 and ending in Feb 2025.
Background Physical performance is an important indicator that reflects current and predicts future health. In this study, we examined the association of alcohol use and depression with grip strength a national sample of middle aged and older Chinese adults. Methods We used the baseline data from the China Health and Retirement Longitudinal Study (CHARLS) and constructed a multivariate linear regression using SAS 9.4 to examine the independent association of alcohol use (never, former, moderate, and at-risk drinkers) and depression with grip strength controlling for socio-economic factors and domestic partner status. Results The study population consisted of 12,488 Chinese adults(mean age 59). The prevalence of ever drinking during lifetime and current at-risk drinking (>14 standard drinks [one standard drink contains 14 grams of pure alcohol] per week) in this population was 25.7% and 15.2% respectively. 28.4% of the study population had depression. Compared with never drinkers, moderate and at-risk alcohol use were independently associated with better grip strength (P<0.0001). Depression was independently negatively associated with grip strength (P<0.0001). Conclusions We found that current alcohol use might be protective of grip strength while depression might be detrimental to grip strength among middle-aged adults. However, the underlying mechanism is unclear. Given the negative impact of alcohol and depression on adults’ overall health, clinicians should assess alcohol use and depression in middle-aged and older patients using validated tools and provide resources. Clinicians should counsel patients that if depression is not managed, patients may suffer from depression associated health consequences such as declined grip strength.
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