To make Quantitative Radiology (QR) a reality in radiological practice, computerized body-wide automatic anatomy recognition (AAR) becomes essential. With the goal of building a general AAR system that is not tied to any specific organ system, body region, or image modality, this paper presents an AAR methodology for localizing and delineating all major organs in different body regions based on fuzzy modeling ideas and a tight integration of fuzzy models with an Iterative Relative Fuzzy Connectedness (IRFC) delineation algorithm. The methodology consists of five main steps: (a) gathering image data for both building models and testing the AAR algorithms from patient image sets existing in our health system; (b) formulating precise definitions of each body region and organ and delineating them following these definitions; (c) building hierarchical fuzzy anatomy models of organs for each body region; (d) recognizing and locating organs in given images by employing the hierarchical models; and (e) delineating the organs following the hierarchy. In Step (c), we explicitly encode object size and positional relationships into the hierarchy and subsequently exploit this information in object recognition in Step (d) and delineation in Step (e). Modality-independent and dependent aspects are carefully separated in model encoding. At the model building stage, a learning process is carried out for rehearsing an optimal threshold-based object recognition method. The recognition process in Step (d) starts from large, well-defined objects and proceeds down the hierarchy in a global to local manner. A fuzzy model-based version of the IRFC algorithm is created by naturally integrating the fuzzy model constraints into the delineation algorithm. The AAR system is tested on three body regions – thorax (on CT), abdomen (on CT and MRI), and neck (on MRI and CT) – involving a total of over 35 organs and 130 data sets (the total used for model building and testing). The training and testing data sets are divided into equal size in all cases except for the neck. Overall the AAR method achieves a mean accuracy of about 2 voxels in localizing non-sparse blob-like objects and most sparse tubular objects. The delineation accuracy in terms of mean false positive and negative volume fractions is 2% and 8%, respectively, for non-sparse objects, and 5% and 15%, respectively, for sparse objects. The two object groups achieve mean boundary distance relative to ground truth of 0.9 and 1.5 voxels, respectively. Some sparse objects – venous system (in the thorax on CT), inferior vena cava (in the abdomen on CT), and mandible and naso-pharynx (in neck on MRI, but not on CT) – pose challenges at all levels, leading to poor recognition and/or delineation results. The AAR method fares quite favorably when compared with methods from the recent literature for liver, kidneys, and spleen on CT images. We conclude that separation of modality-independent from dependent aspects, organization of objects in a hierarchy, encoding of object relationship informati...
Motion graphs have been widely successful in the synthesis of human motions. However, the quality of the generated motions depends heavily on the connectivity of the graphs and the quality of transitions in them. Achieving both of these criteria simultaneously though is difficult. Good connectivity requires transitions between less similar poses, while good motion quality requires transitions only between very similar poses. This paper introduces a new method for building motion graphs. The method first builds a set of interpolated motion clips, which contains many more similar poses than the original data set. The method then constructs a well-connected motion graph (wcMG), by using as little of the interpolated motion clip frames as necessary to provide good connectivity and only smooth transitions. Based on experiments, wcMGs outperform standard motion graphs across different measures, generate good quality motions, allow for high responsiveness in interactive control applications, and do not even require post-processing of the synthesized motions.
Zn and Cl have been found in deposits in municipal solid waste (MSW) boilers and industrial boilers. This leads to the general belief that ZnCl 2 may play a role in corrosion of heat-transfer tubes, owing to its low melting temperature and high corrosivity. In this study, the thermal stability of the compounds ZnCl 2 , ZnSO 4 , and ZnO as well as mixtures of ZnCl 2 and NaCl/ KCl was investigated by means of thermogravimetric analysis/differential scanning calorimetry (TGA/DSC). The reactions of the Zn compounds with SO 2 /SO 3 and HCl were also investigated. The results obtained show that ZnCl 2 melts at 320 °C. Above 400 °C, ZnCl 2 vaporizes and is partly oxidized to ZnO. ZnSO 4 is stable up to 680 °C, at which it decomposes and, subsequently, forms ZnO above 900 °C. ZnO is stable at a much higher temperatures but can be chlorinated to ZnCl 2 in the presence of HCl at temperatures around 300 °C. In the presence of a large amount of NaCl/KCl, which is typically the case in actual boilers, ZnCl 2 reacts with NaCl/KCl to form 2NaCl•ZnCl 2 and 2KCl•ZnCl 2 , respectively. These compounds melt at temperatures lower than NaCl and KCl but higher than ZnCl 2 . The findings show the significance of understanding the thermal stability of various zinc compounds, how they interact with one another, and whether they react with alkali chlorides and other compounds in the deposits to assess the role of Zn in deposit formation and corrosion in boilers burning Zn-containing fuels.
The previous body-region-wise approach can be extended to whole-body torso with similar object localization performance. Combined use of image texture and intensity property yields the best object localization accuracy. In both body-region-wise and whole-body approaches, recognition performance on low-dose CT images reaches levels previously achieved on diagnostic CT images. The best object recognition strategy varies among objects; the proposed framework however allows employing a strategy that is optimal for each object.
Background Automatic segmentation of 3D objects in computed tomography (CT) is challenging. Current methods, based mainly on artificial intelligence (AI) and end‐to‐end deep learning (DL) networks, are weak in garnering high‐level anatomic information, which leads to compromised efficiency and robustness. This can be overcome by incorporating natural intelligence (NI) into AI methods via computational models of human anatomic knowledge. Purpose We formulate a hybrid intelligence (HI) approach that integrates the complementary strengths of NI and AI for organ segmentation in CT images and illustrate performance in the application of radiation therapy (RT) planning via multisite clinical evaluation. Methods The system employs five modules: (i) body region recognition, which automatically trims a given image to a precisely defined target body region; (ii) NI‐based automatic anatomy recognition object recognition (AAR‐R), which performs object recognition in the trimmed image without DL and outputs a localized fuzzy model for each object; (iii) DL‐based recognition (DL‐R), which refines the coarse recognition results of AAR‐R and outputs a stack of 2D bounding boxes (BBs) for each object; (iv) model morphing (MM), which deforms the AAR‐R fuzzy model of each object guided by the BBs output by DL‐R; and (v) DL‐based delineation (DL‐D), which employs the object containment information provided by MM to delineate each object. NI from (ii), AI from (i), (iii), and (v), and their combination from (iv) facilitate the HI system. Results The HI system was tested on 26 organs in neck and thorax body regions on CT images obtained prospectively from 464 patients in a study involving four RT centers. Data sets from one separate independent institution involving 125 patients were employed in training/model building for each of the two body regions, whereas 104 and 110 data sets from the 4 RT centers were utilized for testing on neck and thorax, respectively. In the testing data sets, 83% of the images had limitations such as streak artifacts, poor contrast, shape distortion, pathology, or implants. The contours output by the HI system were compared to contours drawn in clinical practice at the four RT centers by utilizing an independently established ground‐truth set of contours as reference. Three sets of measures were employed: accuracy via Dice coefficient (DC) and Hausdorff boundary distance (HD), subjective clinical acceptability via a blinded reader study, and efficiency by measuring human time saved in contouring by the HI system. Overall, the HI system achieved a mean DC of 0.78 and 0.87 and a mean HD of 2.22 and 4.53 mm for neck and thorax, respectively. It significantly outperformed clinical contouring in accuracy and saved overall 70% of human time over clinical contouring time, whereas acceptability scores varied significantly from site to site for both auto‐contours and clinically drawn contours. Conclusions The HI system is observed to behave like an expert human in robustness in the contouring task but vast...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.