Renal histology results are very scarce in dengue-associated
rhabdomyolysis patients developing acute kidney injury (AKI). We report a case of
dengue fever-induced AKI associated to rhabdomyolysis with a renal biopsy showing
acute tubular necrosis (ATN) and renal deposition of myoglobin. A 28-year-old patient
who presented dengue fever (DF) complicated by severe AKI and rhabdomyolysis is
described. The patient required hemodialysis for three weeks. A renal biopsy revealed
ATN with positive staining for myoglobin in the renal tubuli. The patient was
discharged with recovered renal function. In conclusion, this case report described a
biopsy proven ATN associated to DF-induced rhabdomyolysis, in which renal deposition
of myoglobin was demonstrated. We suggest that serum creatine phosphokinase should be
monitored in DF patients to allow for an early diagnosis of rhabdomyolysis and the
institution of renal protective measures.
The presence of vasculopathy in the kidney allograft at time of transplantation was identified as an important factor independently associated with prolonged DGF. Prolonged DGF negatively impacts 1-year graft function.
Objetivo: Considerando a importância do tema, esse estudo visa buscar na literatura as implicações renais da obesidade. Metodologia: A metodologia selecionada para a realização desse trabalho foi a pesquisa bibliográfica, as bases de dados acessadas de forma on-line foram: Scientific Eletronic Library Online (SCIELO) e US National Library of Medicine National Institutes of Health (PUBMED). Conclusão: No final desse estudo é possível concluir que a obesidade é um fator de risco relevante para a evolução da lesão glomerular, bem como para a progressão para doença renal crônica, tornando assim importante o controle da obesidade para redução da ocorrência da doença renal crônica nesses indivíduos.
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