Background. Lipoprotein(a) [Lp(a)] is a known risk factor for cardiovascular disease, yet its influence on metabolic syndrome (MS) is still controversial. The purpose of this study was to assess the impact generated by this diagnosis in serum Lp(a) concentrations. Materials and Methods. A total of 1807 subjects of both genders (55.3% women and 44.7% men) belonging to the Maracaibo City Metabolic Syndrome Prevalence Study were evaluated. Results were expressed as Mean ± SD, determining differences through Student's t-test and One-Way ANOVA test. Multiple logistic regression models were utilized for analyzing factors associated with elevated serum Lp(a) levels and MS. Total cholesterol and LDL-C were corrected according to Lp(a)-Cholesterol when necessary.
Results. No differences were found in Lp(a) values between genders; P = 0,292. The association between MS and the classification of Lp(a) was statistically significant (χ
2 = 28.33; P < 0,0001), with greater levels in subjects with this diagnosis. In the univariate analysis, subjects with each of the separate diagnostic criteria showed higher serum Lp(a) concentrations, except for hyperglycemia. Conclusions. Lp(a) values exhibit important variations regarding MS and each of its components. Impaired fasting glucose appeared as a protecting factor against elevated Lp(a) concentrations, whereas its association with LDL-C and hs-CRP suggests a potential pro-inflammatory role.
<p style="margin: 0cm 0cm 8pt; text-align: justify;"><span style="font-family: Calibri; font-size: medium;">En un cultivo de lima ácida Tahití Citrus latifolia Tanaka (Rutaceae) con siete años de edad ubicado en El Espinal, Tolima, Colombia, donde predomina un balance hídrico negativo durante todo el año, se evaluó el efecto del riego y la fertilización sobre el rendimiento y la calidad del fruto entre los años 2009 y 2011. Los árboles fueron sometidos a tres láminas de riego en función de la evapotranspiración de referencia (ETo): L1=100 %, L2=70 % y L3=50 %. A su vez, se aplicaron tres tratamientos de fertilización nitrogenada, así: N1=nivel de nitrógeno requerido según el balance nutricional, N2=el doble del nivel de nitrógeno usado para N1 y N3=fertilización del productor. Se evaluaron el rendimiento, el peso del fruto, el diámetro ecuatorial y polar del fruto, el grosor de la cáscara, el peso y el porcentaje de jugo, la acidez, los sólidos solubles y el contenido de vitamina C. El diseño experimental fue de bloques completos al azar en arreglo de parcelas divididas, los datos se analizaron estadísticamente con el paquete SAS, realizando análisis de varianza y comparación de medias. Se presentó una respuesta óptima en riego y calidad del fruto con la interacción riego L1 y la fertilización N2. Se obtuvieron los valores más altos en las variables de respuesta con la lámina de mayor agua aplicada L1, indiferente de la fertilización aplicada, lo que indica que un menor suministro de agua no solo afecta el rendimiento sino también la calidad y minimiza las oportunidades de mercado.</span></p>
To our knowledge, this is the first evidence of the limited impact of modifying the fixed kidney injury definition currently used for acute-on-chronic liver failure.
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