Aim: COVID-19 the novel corona virus that has been characterized as a pandemic; as it spreads all over the world and has so far infected more than 20 million worldwide. In Palestine, the first seven cases were documented on March 5th, 2020 followed by the declaration of the state of emergency. This study aimed to assess knowledge, attitudes and practices toward COVID-19 among Birzeit University students.Subject and methods: A cross sectional study was carried out, a questionnaire was developed based on the WHO, CDC, ECDC recommendations. The questionnaire was distributed online and filled by Birzeit University students. Chi-square testing was performed to check for significant association between KAP and different sociodemographic variables. Binary logistic regression performed to identify and control the confounding factors. Data were analyzed using SPSS (version 22).Results: A total of 665 students have completed the online questionnaire. The mean age was (20.55±3.069) years. Multivariate analysis revealed that males, students from health professions and scientific faculties and those with highly educated parents had manifested a good knowledge level (GKL) about Covid -19. Regarding students’ practices, less negative practices were prompted by students from health professions faculty and the students living at the middle governorate of Palestine compared to north, south and Jerusalem dwellers. With regards to the practices, the vast majority of the participants held a positive and very cautious practice towards the COVID-19 epidemic.Conclusion: Our results revealed that students had variable knowledge regarding Covid-19 and the vast majority depended on the official media briefs in Palestine as a source of information. With regards to practices, positive and cautious practices towards the COVID-19 epidemic were carried out by the vast majority of participants.

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