A series of acylated a-aminophosphine oxides were synthesized by the microwave-assisted Kabachnik-Fields reaction of a series of carboxylic acid amides, formaldehyde and secondary phosphine oxides. To compensate the lower reactivity of the-NH 2 reagents, they had to be used in an excess. The solvolytic condensations furnished the a-aminophosphine oxides in yields of 58-93% after purification by chromatography.
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