Gut microbiota imbalance is found in fecal samples from DN patients, in which
Roseburia intestinalis
is significantly decreased, while
Bacteroides stercoris
is increased. There is a significant correlation between gut microbiota imbalance and clinical indexes related to lipid metabolism, glucose metabolism, and renal function. The gut microbiota may be predictive factors for the development and progression of DN, although further studies are warranted to illustrate their regulatory mechanisms.
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