PurposeTo describe clinical, biochemical and anthropometric profiles in adults with class III obesity classified as metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO).Patients and methodsThis is a cross-sectional study with patients classified as MHO and MUHO according to the NCEP-ATP III. Anthropometric, biochemical and clinical variables were analyzed.ResultsA total of 223 subjects were evaluated and 32.73% were classified as MHO and 67.26% as MUHO, respectively. The insulin resistance homeostasis model (HOMA-IR) showed elevation in the MUHO group (p=0.003) and anthropometric variables were correlated with bone markers [body index mass (BMI) vs phosphorus: r=0.31, p<0.001; BMI vs 25(OH)D: r=−0.31, p=0.041]. Visceral adiposity index was lower in MHO (p=0.001). Negative correlations between inflammatory markers and bone markers were observed in the MHO group (calcium vs C-reactive protein: −0.30, p=0.017; parathyroid hormone vs HOMA-IR: r=−0.28, p=0.017.ConclusionMHO individuals showed important metabolic changes, such as those observed in MUHO, despite lower prevalence and severity. Continuous monitoring of these individuals is suggested, given the transient nature of the MHO phenotype.
Obesity negatively affects the relationship between markers and micronutrients of bone metabolism. Testing the hypothesis that the metabolically healthy obese phenotype might be protected by those alterations was the aim of this study. A cross-sectional study was carried out in adults with class III obesity classified in Metabolically Healthy Obese (MHO) and Metabolically Unhealthy Obese (MUHO), according to the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (NCEP ATP III) criteria. Anthropometric, biochemical, and clinical variables were analyzed for sample characterization. To evaluate bone metabolism, markers (alkaline phosphatase and parathyroid hormone—PTH) and related nutrients (vitamin D, vitamin B12, calcium, phosphorus, magnesium, potassium and zinc) were analyzed. A total of 223 adults with class III obesity aged 41.20 ± 10.15 years were included. The MHO phenotype was identified in 32.73% of the sample. After logistic regression, it was observed that inadequacies of calcium (OR: 4.11; 95% CI: 2.33–6.66), phosphorus (OR: 3.03; 95% CI: 1.98–5.79), vitamin D (OR: 5.01; 95% CI: 2.92–6.71) and PTH (OR: 5.45; 95% CI: 4.49–6.74) were significantly higher in the MUHO group compared to the MHO Group. This study showed that the MHO phenotype does not protect adults from alterations in markers and micronutrients of bone metabolism. However, the MUHO phenotype presents a higher risk for alterations related to bone metabolism, which can favor the emergence of metabolic bone diseases.
RESUMOIntrodução: No futsal ocorre uma grande produção de suor com a consequente perda de líquido e eletrólitos. Tal perda pode ocasionar diversos transtornos orgânicos, incluindo a desidratação, capaz de comprometer o desempenho durante o exercício e prejudicar a saúde. Objetivo: Avaliar a perda hídrica e os hábitos de hidratação de atletas universitários de futsal competitivo. Métodos: Os dados foram coletados em dois treinos não consecutivos (A e B), nos quais foram verificadas as variações do peso pré e pós-treino de 17 atletas do sexo masculino. Aplicaram-se fórmulas específicas para avaliação das variações. Os atletas consumiram 360 ml de água 40 minutos antes dos treinos, não sendo permitida a ingestão de outros líquidos nem a excreção urinária. Os hábitos de hidratação foram identificados por meio de um questionário contendo questões objetivas relacionadas ao tema. Resultados: A perda hídrica relativa do treino A foi de 1,02 ± 0,28 kg e a do treino B, de 1,18 ± 0,44 kg, correspondendo em desidratação percentual de 1,40 ± 0,38% e 1,59 ± 0,56%, respectivamente. Houve diferença significativa entre a taxa de sudorese do treino A com relação ao B (p < 0,0474). Todo o grupo (100%) costumava se hidratar durante treinos e competições; 52,95% mostraram despreocupação com o tipo de bebida ingerida; a água é a solução hidratante mais consumida (100%), seguida por suco natural (88,23%) e café (76,47%). Os sintomas mais relevantes decorrentes da desidratação foram: sede intensa (88,23%), sensação de perda de força (82,35%) e fadiga (82,35%). Conclusão: A perda hídrica evidenciada nos treinos foi significativa, já que implica início de desidratação. A maioria dos atletas tem hábitos hídricos inadequados, principalmente quando comparados ao nível de entendimento sobre o tema. Sugere-se o reforço de orientações e estabelecimento de estratégias, visando ratificar a seriedade do assunto e atenuar os possíveis riscos associados ao calor. Descritores
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
334 Leonard St
Brooklyn, NY 11211
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.